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REC drives recombination to repair double-strand breaks in animal mtDNA

Mechanisms that safeguard mitochondrial DNA (mtDNA) limit the accumulation of mutations linked to mitochondrial and age-related diseases. Yet, pathways that repair double-strand breaks (DSBs) in animal mitochondria are poorly understood. By performing a candidate screen for mtDNA repair proteins, we...

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Detalles Bibliográficos
Autores principales:	Klucnika, Anna, Mu, Peiqiang, Jezek, Jan, McCormack, Matthew, Di, Ying, Bradshaw, Charles R., Ma, Hansong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652705/ https://www.ncbi.nlm.nih.gov/pubmed/36355348 http://dx.doi.org/10.1083/jcb.202201137

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