ER–endosome contacts master the ins and outs of secretory endosomes

What defines whether an endosome follows the degradative pathway or fuses with the plasma membrane to release exosomes? In this issue of JCB, Fredrik Verweij and colleagues (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202112032) demonstrate how secretory endosomes are guided by ER–endosome conta...

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Detalles Bibliográficos
Autores principales: Wenzel, Eva Maria, Raiborg, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652769/
https://www.ncbi.nlm.nih.gov/pubmed/36355088
http://dx.doi.org/10.1083/jcb.202210033
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author Wenzel, Eva Maria
Raiborg, Camilla
author_facet Wenzel, Eva Maria
Raiborg, Camilla
author_sort Wenzel, Eva Maria
collection PubMed
description What defines whether an endosome follows the degradative pathway or fuses with the plasma membrane to release exosomes? In this issue of JCB, Fredrik Verweij and colleagues (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202112032) demonstrate how secretory endosomes are guided by ER–endosome contacts to take a cellular detour and several identity transitions for efficient exosome release.
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spelling pubmed-96527692023-05-10 ER–endosome contacts master the ins and outs of secretory endosomes Wenzel, Eva Maria Raiborg, Camilla J Cell Biol Spotlight What defines whether an endosome follows the degradative pathway or fuses with the plasma membrane to release exosomes? In this issue of JCB, Fredrik Verweij and colleagues (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202112032) demonstrate how secretory endosomes are guided by ER–endosome contacts to take a cellular detour and several identity transitions for efficient exosome release. Rockefeller University Press 2022-11-10 /pmc/articles/PMC9652769/ /pubmed/36355088 http://dx.doi.org/10.1083/jcb.202210033 Text en © 2022 Wenzel and Raiborg https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Wenzel, Eva Maria
Raiborg, Camilla
ER–endosome contacts master the ins and outs of secretory endosomes
title ER–endosome contacts master the ins and outs of secretory endosomes
title_full ER–endosome contacts master the ins and outs of secretory endosomes
title_fullStr ER–endosome contacts master the ins and outs of secretory endosomes
title_full_unstemmed ER–endosome contacts master the ins and outs of secretory endosomes
title_short ER–endosome contacts master the ins and outs of secretory endosomes
title_sort er–endosome contacts master the ins and outs of secretory endosomes
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652769/
https://www.ncbi.nlm.nih.gov/pubmed/36355088
http://dx.doi.org/10.1083/jcb.202210033
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