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BICOSS: Bayesian iterative conditional stochastic search for GWAS

BACKGROUND: Single marker analysis (SMA) with linear mixed models for genome wide association studies has uncovered the contribution of genetic variants to many observed phenotypes. However, SMA has weak false discovery control. In addition, when a few variants have large effect sizes, SMA has low s...

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Detalles Bibliográficos
Autores principales: Williams, Jacob, Ferreira, Marco A. R., Ji, Tieming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652902/
https://www.ncbi.nlm.nih.gov/pubmed/36371147
http://dx.doi.org/10.1186/s12859-022-05030-0