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BICOSS: Bayesian iterative conditional stochastic search for GWAS
BACKGROUND: Single marker analysis (SMA) with linear mixed models for genome wide association studies has uncovered the contribution of genetic variants to many observed phenotypes. However, SMA has weak false discovery control. In addition, when a few variants have large effect sizes, SMA has low s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652902/ https://www.ncbi.nlm.nih.gov/pubmed/36371147 http://dx.doi.org/10.1186/s12859-022-05030-0 |