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Assessing the relative importance of bacterial resistance, persistence and hyper-mutation for antibiotic treatment failure
To curb the rising threat of antimicrobial resistance, we need to understand the routes to antimicrobial treatment failure. Bacteria can survive treatment by using both genetic and phenotypic mechanisms to diminish the effect of antimicrobials. We assemble empirical data showing that, for example, P...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653239/ https://www.ncbi.nlm.nih.gov/pubmed/36350213 http://dx.doi.org/10.1098/rspb.2022.1300 |