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Assessing the relative importance of bacterial resistance, persistence and hyper-mutation for antibiotic treatment failure

To curb the rising threat of antimicrobial resistance, we need to understand the routes to antimicrobial treatment failure. Bacteria can survive treatment by using both genetic and phenotypic mechanisms to diminish the effect of antimicrobials. We assemble empirical data showing that, for example, P...

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Detalles Bibliográficos
Autores principales: Witzany, Christopher, Regoes, Roland R., Igler, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653239/
https://www.ncbi.nlm.nih.gov/pubmed/36350213
http://dx.doi.org/10.1098/rspb.2022.1300