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Reactions of cisplatin and oxaliplatin with penicillin G: implications for drug inactivation and biological activity

Determination of the toxicity of compounds toward cancer cells is a frequent procedure in drug discovery. For metal complexes, which are often reactive prodrugs, care has to be taken to consider reactions with components of the cell culture medium that might change the speciation of the metal comple...

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Detalles Bibliográficos
Autores principales: Wang, Fang-Xin, Prokes, Ivan, Song, Lijiang, Shi, Huayun, Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653338/
https://www.ncbi.nlm.nih.gov/pubmed/36153767
http://dx.doi.org/10.1007/s00775-022-01958-z

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