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Reactions of cisplatin and oxaliplatin with penicillin G: implications for drug inactivation and biological activity
Determination of the toxicity of compounds toward cancer cells is a frequent procedure in drug discovery. For metal complexes, which are often reactive prodrugs, care has to be taken to consider reactions with components of the cell culture medium that might change the speciation of the metal comple...
Autores principales: | Wang, Fang-Xin, Prokes, Ivan, Song, Lijiang, Shi, Huayun, Sadler, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653338/ https://www.ncbi.nlm.nih.gov/pubmed/36153767 http://dx.doi.org/10.1007/s00775-022-01958-z |
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