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Behavioral and neurophysiological correlates of emotional face processing in borderline personality disorder: are there differences between men and women?

Emotional dysregulation is a core feature of borderline personality disorder (BPD); it is, for example, known to influence one’s ability to read other people’s facial expressions. We investigated behavioral and neurophysiological foundations of emotional face processing in individuals with BPD and i...

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Autores principales: Andermann, Martin, Izurieta Hidalgo, Natalie A., Rupp, André, Schmahl, Christian, Herpertz, Sabine C., Bertsch, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653371/
https://www.ncbi.nlm.nih.gov/pubmed/35661904
http://dx.doi.org/10.1007/s00406-022-01434-4
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author Andermann, Martin
Izurieta Hidalgo, Natalie A.
Rupp, André
Schmahl, Christian
Herpertz, Sabine C.
Bertsch, Katja
author_facet Andermann, Martin
Izurieta Hidalgo, Natalie A.
Rupp, André
Schmahl, Christian
Herpertz, Sabine C.
Bertsch, Katja
author_sort Andermann, Martin
collection PubMed
description Emotional dysregulation is a core feature of borderline personality disorder (BPD); it is, for example, known to influence one’s ability to read other people’s facial expressions. We investigated behavioral and neurophysiological foundations of emotional face processing in individuals with BPD and in healthy controls, taking participants’ sex into account. 62 individuals with BPD (25 men, 37 women) and 49 healthy controls (20 men, 29 women) completed an emotion classification task with faces depicting blends of angry and happy expressions while the electroencephalogram was recorded. The cortical activity (late positive potential, P3/LPP) was evaluated using source modeling. Compared to healthy controls, individuals with BPD responded slower to happy but not to angry faces; further, they showed more anger ratings in happy but not in angry faces, especially in those with high ambiguity. Men had lower anger ratings than women and responded slower to angry but not happy faces. The P3/LPP was larger in healthy controls than in individuals with BPD, and larger in women than in men; moreover, women but not men produced enlarged P3/LPP responses to angry vs. happy faces. Sex did not interact with behavioral or P3/LPP-related differences between healthy controls and individuals with BPD. Together, BPD-related alterations in behavioral and P3/LPP correlates of emotional face processing exist in both men and women, supposedly without sex-related interactions. Results point to a general ‘negativity bias’ in women. Source modeling is well suited to investigate effects of participant and stimulus characteristics on the P3/LPP generators.
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spelling pubmed-96533712022-11-15 Behavioral and neurophysiological correlates of emotional face processing in borderline personality disorder: are there differences between men and women? Andermann, Martin Izurieta Hidalgo, Natalie A. Rupp, André Schmahl, Christian Herpertz, Sabine C. Bertsch, Katja Eur Arch Psychiatry Clin Neurosci Original Paper Emotional dysregulation is a core feature of borderline personality disorder (BPD); it is, for example, known to influence one’s ability to read other people’s facial expressions. We investigated behavioral and neurophysiological foundations of emotional face processing in individuals with BPD and in healthy controls, taking participants’ sex into account. 62 individuals with BPD (25 men, 37 women) and 49 healthy controls (20 men, 29 women) completed an emotion classification task with faces depicting blends of angry and happy expressions while the electroencephalogram was recorded. The cortical activity (late positive potential, P3/LPP) was evaluated using source modeling. Compared to healthy controls, individuals with BPD responded slower to happy but not to angry faces; further, they showed more anger ratings in happy but not in angry faces, especially in those with high ambiguity. Men had lower anger ratings than women and responded slower to angry but not happy faces. The P3/LPP was larger in healthy controls than in individuals with BPD, and larger in women than in men; moreover, women but not men produced enlarged P3/LPP responses to angry vs. happy faces. Sex did not interact with behavioral or P3/LPP-related differences between healthy controls and individuals with BPD. Together, BPD-related alterations in behavioral and P3/LPP correlates of emotional face processing exist in both men and women, supposedly without sex-related interactions. Results point to a general ‘negativity bias’ in women. Source modeling is well suited to investigate effects of participant and stimulus characteristics on the P3/LPP generators. Springer Berlin Heidelberg 2022-06-05 2022 /pmc/articles/PMC9653371/ /pubmed/35661904 http://dx.doi.org/10.1007/s00406-022-01434-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Paper
Andermann, Martin
Izurieta Hidalgo, Natalie A.
Rupp, André
Schmahl, Christian
Herpertz, Sabine C.
Bertsch, Katja
Behavioral and neurophysiological correlates of emotional face processing in borderline personality disorder: are there differences between men and women?
title Behavioral and neurophysiological correlates of emotional face processing in borderline personality disorder: are there differences between men and women?
title_full Behavioral and neurophysiological correlates of emotional face processing in borderline personality disorder: are there differences between men and women?
title_fullStr Behavioral and neurophysiological correlates of emotional face processing in borderline personality disorder: are there differences between men and women?
title_full_unstemmed Behavioral and neurophysiological correlates of emotional face processing in borderline personality disorder: are there differences between men and women?
title_short Behavioral and neurophysiological correlates of emotional face processing in borderline personality disorder: are there differences between men and women?
title_sort behavioral and neurophysiological correlates of emotional face processing in borderline personality disorder: are there differences between men and women?
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653371/
https://www.ncbi.nlm.nih.gov/pubmed/35661904
http://dx.doi.org/10.1007/s00406-022-01434-4
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