Cargando…

Durability and cross-reactivity of immune responses induced by a plant-based virus-like particle vaccine for COVID-19

As the SARS-CoV-2 pandemic evolves, vaccine evaluation needs to include consideration of both durability and cross-reactivity. This report expands on previously reported results from a Phase 1 trial of an AS03-adjuvanted, plant-based coronavirus-like particle (CoVLP) displaying the spike (S) glycopr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gobeil, Philipe, Pillet, Stéphane, Boulay, Iohann, Charland, Nathalie, Lorin, Aurélien, Cheng, Matthew P., Vinh, Donald C., Boutet, Philippe, Van Der Most, Robbert, Roman, François, Ceregido, Maria Angeles, Landry, Nathalie, D’Aoust, Marc-André, Ward, Brian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653456/ https://www.ncbi.nlm.nih.gov/pubmed/36371408 http://dx.doi.org/10.1038/s41467-022-34728-1

Ejemplares similares

Safety and immunogenicity of an AS03-adjuvanted plant-based SARS-CoV-2 vaccine in Adults with and without Comorbidities
por: Charland, Nathalie, et al.
Publicado: (2022)

Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
por: Ward, Brian J., et al.
Publicado: (2021)

Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine
por: Hager, Karen J., et al.
Publicado: (2022)

The establishment of surrogates and correlates of protection: Useful tools for the licensure of effective influenza vaccines?
por: Ward, Brian J., et al.
Publicado: (2018)

Robust induction of functional humoral response by a plant-derived Coronavirus-like particle vaccine candidate for COVID-19
por: Kaplonek, Paulina, et al.
Publicado: (2023)

Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates
por: Pillet, Stéphane, et al.
Publicado: (2022)

Elimination of receptor binding by influenza hemagglutinin improves vaccine-induced immunity
por: Hendin, Hilary E., et al.
Publicado: (2022)

A plant-derived VLP influenza vaccine elicits a balanced immune response even in very old mice with co-morbidities
por: Hodgins, Breanna, et al.
Publicado: (2019)

Prime-pull vaccination with a plant-derived virus-like particle influenza vaccine elicits a broad immune response and protects aged mice from death and frailty after challenge
por: Hodgins, Breanna, et al.
Publicado: (2019)

Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages
por: Makarkov, Alexander I., et al.
Publicado: (2019)

Management of inflammatory bowel disease with Clostridium difficile infection
por: D’Aoust, Julie, et al.
Publicado: (2017)

Immunogenicity and safety of a quadrivalent plant-derived virus like particle influenza vaccine candidate—Two randomized Phase II clinical trials in 18 to 49 and ≥50 years old adults
por: Pillet, Stéphane, et al.
Publicado: (2019)

Humoral and cell-mediated immune responses to H5N1 plant-made virus-like particle vaccine are differentially impacted by alum and GLA-SE adjuvants in a Phase 2 clinical trial
por: Pillet, Stéphane, et al.
Publicado: (2018)

Vertebral Osteomyelitis: An Under-Recognized Infectious Complication in Patients on Home Parenteral Nutrition
por: Huard, Genevieve, et al.
Publicado: (2014)

Herpes Simplex Virus γ34.5 Interferes with Autophagosome Maturation and Antigen Presentation in Dendritic Cells
por: Gobeil, Philipe A. M., et al.
Publicado: (2012)

Increasing the Number of Faculty With CNE(®) Certification: A Statewide Initiative
por: Daw, Peggy, et al.
Publicado: (2022)

Explainable COVID-19 Detection Based on Chest X-rays Using an End-to-End RegNet Architecture
por: Chetoui, Mohamed, et al.
Publicado: (2023)

Broad neutralization against SARS-CoV-2 variants induced by ancestral and B.1.351 AS03-Adjuvanted recombinant Plant-Derived Virus-Like particle vaccines
por: Dubé, Charlotte, et al.
Publicado: (2022)

Durability of Blended Cements Made with Reactive Aggregates
por: Menéndez, Esperanza, et al.
Publicado: (2021)

Transient and durable T cell reactivity after COVID-19
por: Martner, Anna, et al.
Publicado: (2022)

Protection of Recombinant Mammalian Antibodies from Development-Dependent Proteolysis in Leaves of Nicotiana benthamiana
por: Robert, Stéphanie, et al.
Publicado: (2013)

Piperlongumine promotes death of retinoblastoma cancer cells
por: Allaman-Pillet, Nathalie, et al.
Publicado: (2021)

Recombinant protein susceptibility to proteolysis in the plant cell secretory pathway is pH‐dependent
por: Jutras, Philippe V., et al.
Publicado: (2018)

Prevalence and Characteristics of Non–US-Born and US-Born Health Care Professionals, 2010-2018
por: Commodore-Mensah, Yvonne, et al.
Publicado: (2021)

Assessing the benefits of early pandemic influenza vaccine availability: a case study for Ontario, Canada
por: Champredon, David, et al.
Publicado: (2018)

UNDERSTANDING AND ADDRESSING IMMUNOSENESCENCE
por: Van Der Most, Robbert
Publicado: (2019)

Durable and controlled depletion of neutrophils in mice
por: Boivin, Gael, et al.
Publicado: (2020)

Chemically reactive protein nanoparticles for synthesis of a durable and deformable superhydrophobic material
por: Shome, Arpita, et al.
Publicado: (2019)

Revealing the role of ionic liquids in promoting fuel cell catalysts reactivity and durability
por: Avid, Arezoo, et al.
Publicado: (2022)

Safety of reduced antigen content diphtheria-tetanus-acellular pertussis vaccine when administered during pregnancy as part of the maternal immunization program in Brazil: a single center, observational, retrospective, cohort study
por: Sancovski, Mauro, et al.
Publicado: (2019)

Bigh3 silencing increases retinoblastoma tumor growth in the murine SV40-TAg-Rb model
por: Allaman-Pillet, Nathalie, et al.
Publicado: (2017)

Recurrent floods and prevalence of diarrhea among under five children: observations from Bahraich district, Uttar Pradesh, India
por: Joshi, Pooran C., et al.
Publicado: (2011)

The need of an environmental justice approach for wastewater based epidemiology for rural and disadvantaged communities: A review in California
por: Medina, Clara Y., et al.
Publicado: (2022)

In planta expression of active bacterial GDP‐6‐deoxy‐d‐lyxo‐4‐hexulose reductase for glycan modulation
por: Kogelmann, Benjamin, et al.
Publicado: (2023)

The adjuvant GLA-AF enhances human intradermal vaccine responses
por: Carter, Darrick, et al.
Publicado: (2018)

Evaluation of Touch and Durability of Cotton Knit Fabrics Treated with Reactive Urethane-Silicone Softener
por: Cho, Hang Sung, et al.
Publicado: (2022)

Coronavac inactivated vaccine triggers durable, cross-reactive Fc-mediated phagocytosis activities
por: Wang, Lili, et al.
Publicado: (2023)

KIAA1462, A Coronary Artery Disease Associated Gene, Is a Candidate Gene for Late Onset Alzheimer Disease in APOE Carriers
por: Murdock, Deborah G., et al.
Publicado: (2013)

Seeking the environmental source of Leptospirosis reveals durable bacterial viability in river soils
por: Thibeaux, Roman, et al.
Publicado: (2017)

Insight into the durability of plant resistance to aphids from a demo‐genetic study of Aphis gossypii in melon crops
por: Thomas, Sophie, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0en5u3jdbfvi5q9lginetr8dah