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Gene–gene interaction detection with deep learning

The extent to which genetic interactions affect observed phenotypes is generally unknown because current interaction detection approaches only consider simple interactions between top SNPs of genes. We introduce an open-source framework for increasing the power of interaction detection by considerin...

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Detalles Bibliográficos
Autores principales:	Cui, Tianyu, El Mekkaoui, Khaoula, Reinvall, Jaakko, Havulinna, Aki S., Marttinen, Pekka, Kaski, Samuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653457/ https://www.ncbi.nlm.nih.gov/pubmed/36371468 http://dx.doi.org/10.1038/s42003-022-04186-y

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