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A digital twin for (64)Cu production with cyclotron and solid target system
One method for finding reliable and cost-effective solutions for designing radioisotope production systems is represented by the “digital twin” philosophy of design. Looking at cyclotron solid targets, uncertainties of the particle beam, material composition and geometry play a crucial role in deter...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653460/ https://www.ncbi.nlm.nih.gov/pubmed/36371472 http://dx.doi.org/10.1038/s41598-022-23048-5 |
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author | Isolan, Lorenzo Malinconico, Mario Tieu, William Hollis, Courtney Testa, Marco Melandri, Matteo Brunetti, Alessandro Sumini, Marco |
author_facet | Isolan, Lorenzo Malinconico, Mario Tieu, William Hollis, Courtney Testa, Marco Melandri, Matteo Brunetti, Alessandro Sumini, Marco |
author_sort | Isolan, Lorenzo |
collection | PubMed |
description | One method for finding reliable and cost-effective solutions for designing radioisotope production systems is represented by the “digital twin” philosophy of design. Looking at cyclotron solid targets, uncertainties of the particle beam, material composition and geometry play a crucial role in determining the results. The difference between what has been designed and what can be effectively manufactured, where processes such as electroplating are poorly controllable and generate large non-uniformities in deposition, must also be considered. A digital twin, where the target geometry is 3D scanned from real models, can represent a good compromise for connecting “ideal” and “real” worlds. Looking at the (64)Ni(p,n)(64)Cu reaction, different Unstructured-Mesh MCNP6 models have been built starting from the 3D solid target system designed and put into operation by COMECER. A characterization has been performed considering the designed ideal target and a 3D scan of a real manufactured target measured with a ZEISS contact probe. Libraries and physics models have been also tested due to limited cross-section data. Proton spectra in the target volume, 3D proton-neutron-photon flux maps, average energies, power to be dissipated, shut-down dose-rate, (64)Cu yield compared with various sources of experimental data and beam axial shifting impact, have been estimated. A digital twin of the (64)Ni(p,n)(64)Cu production device has been characterized, considering the real measured target geometry, paving the way for a fully integrated model suitable also for thermal, structural or fluid-dynamic analyses. |
format | Online Article Text |
id | pubmed-9653460 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-96534602022-11-15 A digital twin for (64)Cu production with cyclotron and solid target system Isolan, Lorenzo Malinconico, Mario Tieu, William Hollis, Courtney Testa, Marco Melandri, Matteo Brunetti, Alessandro Sumini, Marco Sci Rep Article One method for finding reliable and cost-effective solutions for designing radioisotope production systems is represented by the “digital twin” philosophy of design. Looking at cyclotron solid targets, uncertainties of the particle beam, material composition and geometry play a crucial role in determining the results. The difference between what has been designed and what can be effectively manufactured, where processes such as electroplating are poorly controllable and generate large non-uniformities in deposition, must also be considered. A digital twin, where the target geometry is 3D scanned from real models, can represent a good compromise for connecting “ideal” and “real” worlds. Looking at the (64)Ni(p,n)(64)Cu reaction, different Unstructured-Mesh MCNP6 models have been built starting from the 3D solid target system designed and put into operation by COMECER. A characterization has been performed considering the designed ideal target and a 3D scan of a real manufactured target measured with a ZEISS contact probe. Libraries and physics models have been also tested due to limited cross-section data. Proton spectra in the target volume, 3D proton-neutron-photon flux maps, average energies, power to be dissipated, shut-down dose-rate, (64)Cu yield compared with various sources of experimental data and beam axial shifting impact, have been estimated. A digital twin of the (64)Ni(p,n)(64)Cu production device has been characterized, considering the real measured target geometry, paving the way for a fully integrated model suitable also for thermal, structural or fluid-dynamic analyses. Nature Publishing Group UK 2022-11-12 /pmc/articles/PMC9653460/ /pubmed/36371472 http://dx.doi.org/10.1038/s41598-022-23048-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Isolan, Lorenzo Malinconico, Mario Tieu, William Hollis, Courtney Testa, Marco Melandri, Matteo Brunetti, Alessandro Sumini, Marco A digital twin for (64)Cu production with cyclotron and solid target system |
title | A digital twin for (64)Cu production with cyclotron and solid target system |
title_full | A digital twin for (64)Cu production with cyclotron and solid target system |
title_fullStr | A digital twin for (64)Cu production with cyclotron and solid target system |
title_full_unstemmed | A digital twin for (64)Cu production with cyclotron and solid target system |
title_short | A digital twin for (64)Cu production with cyclotron and solid target system |
title_sort | digital twin for (64)cu production with cyclotron and solid target system |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653460/ https://www.ncbi.nlm.nih.gov/pubmed/36371472 http://dx.doi.org/10.1038/s41598-022-23048-5 |
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