APOE E4 is associated with impaired self-declared cognition but not disease risk or age of onset in Nigerians with Parkinson’s disease

The relationship between APOE polymorphisms and Parkinson’s disease (PD) in black Africans has not been previously investigated. We evaluated the association between APOE polymorphic variability and self-declared cognition in 1100 Nigerians with PD and 1097 age-matched healthy controls. Cognition in...

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Autores principales: Okubadejo, Njideka U., Okunoye, Olaitan, Ojo, Oluwadamilola O., Arabambi, Babawale, Akinyemi, Rufus O., Osaigbovo, Godwin O., Abubakar, Sani A., Iwuozo, Emmanuel U., Wahab, Kolawole W., Agabi, Osigwe P., Agulanna, Uchechi, Imarhiagbe, Frank A., Abiodun, Oladunni V., Achoru, Charles O., Adebowale, Akintunde A., Adeniji, Olaleye, Akpekpe, John E., Ali, Mohammed W., Ani-Osheku, Ifeyinwa, Arigbodi, Ohwotemu, Balarabe, Salisu A., Bello, Abiodun H., Ekenze, Oluchi S., Erameh, Cyril O., Farombi, Temitope H., Fawale, Michael B., Komolafe, Morenikeji A., Nwani, Paul O., Nwazor, Ernest O., Nyandaiti, Yakub, Obehighe, Emmanuel E., Obiabo, Yahaya O., Odeniyi, Olanike A., Odiase, Francis E., Ojini, Francis I., Onwuegbuzie, Gerald A., Osemwegie, Nosakhare, Oshinaike, Olajumoke O., Otubogun, Folajimi M., Oyakhire, Shyngle I., Taiwo, Funlola T., Williams, Uduak E., Ozomma, Simon, Zubair, Yusuf, Hernandez, Dena, Bandres-Ciga, Sara, Blauwendraat, Cornelis, Singleton, Andrew, Houlden, Henry, Hardy, John, Rizig, Mie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653490/
https://www.ncbi.nlm.nih.gov/pubmed/36371506
http://dx.doi.org/10.1038/s41531-022-00411-x

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