IL-33 induces thymic involution-associated naive T cell aging and impairs host control of severe infection

Severe infection commonly results in immunosuppression, which leads to impaired pathogen clearance or increased secondary infection in both humans and animals. However, the exact mechanisms remain poorly understood. Here, we demonstrate that IL-33 results in immunosuppression by inducing thymic invo...

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Detalles Bibliográficos
Autores principales: Xu, Lei, Wei, Chuan, Chen, Ying, Wu, Yue, Shou, Xiaoli, Chen, Wenjie, Lu, Di, Sun, Haoran, Li, Wei, Yu, Beibei, Wang, Xiaowei, Zhang, Xiaojun, Yu, Yanxiong, Lei, Zhigang, Tang, Rui, Zhu, Jifeng, Li, Yalin, Lu, Linrong, Zhou, Hong, Zhou, Sha, Su, Chuan, Chen, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653498/
https://www.ncbi.nlm.nih.gov/pubmed/36371464
http://dx.doi.org/10.1038/s41467-022-34660-4

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