The Integrated Stress Response Is Tumorigenic and Constitutes a Therapeutic Liability in Somatotroph Adenomas

Somatotroph adenomas are the leading cause of acromegaly, with the nearly sparsely granulated somatotroph subtype belonging to high-risk adenomas, and they are less responsive to medical treatment. The integrated stress response (ISR) is an essential stress-support pathway increasingly recognized as...

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Detalles Bibliográficos
Autores principales: Li, Zhenye, Chen, Yiyuan, Yao, Xiaohui, Liu, Qian, Zhu, Haibo, Zhang, Yazhuo, Feng, Jie, Gao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653568/
https://www.ncbi.nlm.nih.gov/pubmed/36361871
http://dx.doi.org/10.3390/ijms232113067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653568/
https://www.ncbi.nlm.nih.gov/pubmed/36361871
http://dx.doi.org/10.3390/ijms232113067

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