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Recent Advances in the Application of Natural and Synthetic Polymer-Based Scaffolds in Musculoskeletal Regeneration

The musculoskeletal system plays a critical role in providing the physical scaffold and movement to the mammalian body. Musculoskeletal disorders severely affect mobility and quality of life and pose a heavy burden to society. This new field of musculoskeletal tissue engineering has great potential...

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Detalles Bibliográficos
Autores principales: Ye, Bing, Wu, Bin, Su, Yanlin, Sun, Tingfang, Guo, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653578/
https://www.ncbi.nlm.nih.gov/pubmed/36365559
http://dx.doi.org/10.3390/polym14214566
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author Ye, Bing
Wu, Bin
Su, Yanlin
Sun, Tingfang
Guo, Xiaodong
author_facet Ye, Bing
Wu, Bin
Su, Yanlin
Sun, Tingfang
Guo, Xiaodong
author_sort Ye, Bing
collection PubMed
description The musculoskeletal system plays a critical role in providing the physical scaffold and movement to the mammalian body. Musculoskeletal disorders severely affect mobility and quality of life and pose a heavy burden to society. This new field of musculoskeletal tissue engineering has great potential as an alternative approach to treating large musculoskeletal defects. Natural and synthetic polymers are widely used in musculoskeletal tissue engineering owing to their good biocompatibility and biodegradability. Even more promising is the use of natural and synthetic polymer composites, as well as the combination of polymers and inorganic materials, to repair musculoskeletal tissue. Therefore, this review summarizes the progress of polymer-based scaffolds for applications of musculoskeletal tissue engineering and briefly discusses the challenges and future perspectives.
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spelling pubmed-96535782022-11-15 Recent Advances in the Application of Natural and Synthetic Polymer-Based Scaffolds in Musculoskeletal Regeneration Ye, Bing Wu, Bin Su, Yanlin Sun, Tingfang Guo, Xiaodong Polymers (Basel) Review The musculoskeletal system plays a critical role in providing the physical scaffold and movement to the mammalian body. Musculoskeletal disorders severely affect mobility and quality of life and pose a heavy burden to society. This new field of musculoskeletal tissue engineering has great potential as an alternative approach to treating large musculoskeletal defects. Natural and synthetic polymers are widely used in musculoskeletal tissue engineering owing to their good biocompatibility and biodegradability. Even more promising is the use of natural and synthetic polymer composites, as well as the combination of polymers and inorganic materials, to repair musculoskeletal tissue. Therefore, this review summarizes the progress of polymer-based scaffolds for applications of musculoskeletal tissue engineering and briefly discusses the challenges and future perspectives. MDPI 2022-10-27 /pmc/articles/PMC9653578/ /pubmed/36365559 http://dx.doi.org/10.3390/polym14214566 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ye, Bing
Wu, Bin
Su, Yanlin
Sun, Tingfang
Guo, Xiaodong
Recent Advances in the Application of Natural and Synthetic Polymer-Based Scaffolds in Musculoskeletal Regeneration
title Recent Advances in the Application of Natural and Synthetic Polymer-Based Scaffolds in Musculoskeletal Regeneration
title_full Recent Advances in the Application of Natural and Synthetic Polymer-Based Scaffolds in Musculoskeletal Regeneration
title_fullStr Recent Advances in the Application of Natural and Synthetic Polymer-Based Scaffolds in Musculoskeletal Regeneration
title_full_unstemmed Recent Advances in the Application of Natural and Synthetic Polymer-Based Scaffolds in Musculoskeletal Regeneration
title_short Recent Advances in the Application of Natural and Synthetic Polymer-Based Scaffolds in Musculoskeletal Regeneration
title_sort recent advances in the application of natural and synthetic polymer-based scaffolds in musculoskeletal regeneration
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653578/
https://www.ncbi.nlm.nih.gov/pubmed/36365559
http://dx.doi.org/10.3390/polym14214566
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