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A Balance between Transmembrane-Mediated ER/Golgi Retention and Forward Trafficking Signals in Glycophorin-Anion Exchanger-1 Interaction

Anion exchanger-1 (AE1) is the main erythroid Cl(−)/HCO(3)(−) transporter that supports CO(2) transport. Glycophorin A (GPA), a component of the AE1 complexes, facilitates AE1 expression and anion transport, but Glycophorin B (GPB) does not. Here, we dissected the structural components of GPA/GPB in...

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Detalles Bibliográficos
Autores principales: Hsu, Kate, Lee, Ting-Ying, Lin, Jian-Yi, Chen, Pin-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653601/
https://www.ncbi.nlm.nih.gov/pubmed/36359907
http://dx.doi.org/10.3390/cells11213512