Cargando…

Tau Protein as Therapeutic Target for Cancer? Focus on Glioblastoma

SIMPLE SUMMARY: Tau protein is a microtubule-associated protein, widely known for its role in neurodegenerative diseases. Recent studies show that Tau can also be involved in the progression of many cancers as well as in cancer treatment resistance. This work overviews the role of Tau in tumorigenic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hedna, Rayane, Kovacic, Hervé, Pagano, Alessandra, Peyrot, Vincent, Robin, Maxime, Devred, François, Breuzard, Gilles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653627/ https://www.ncbi.nlm.nih.gov/pubmed/36358803 http://dx.doi.org/10.3390/cancers14215386

Ejemplares similares

2-Aminothiazole-Flavonoid Hybrid Derivatives Binding to Tau Protein and Responsible for Antitumor Activity in Glioblastoma
por: Hedna, Rayane, et al.
Publicado: (2023)

Tau Regulates Glioblastoma Progression, 3D Cell Organization, Growth and Migration via the PI3K-AKT Axis
por: Pagano, Alessandra, et al.
Publicado: (2021)

Myotoxin-3 from the Pacific Rattlesnake Crotalus oreganus oreganus Venom Is a New Microtubule-Targeting Agent
por: González García, María Cecilia, et al.
Publicado: (2022)

Two Tau binding sites on tubulin revealed by thiol-disulfide exchanges
por: Martinho, Marlène, et al.
Publicado: (2018)

Stathmin Potentiates Vinflunine and Inhibits Paclitaxel Activity
por: Malesinski, Soazig, et al.
Publicado: (2015)

Tau antagonizes end-binding protein tracking at microtubule ends through a phosphorylation-dependent mechanism
por: Ramirez-Rios, Sacnicte, et al.
Publicado: (2016)

Quantitative Analysis of Tau-Microtubule Interaction Using FRET
por: Di Maïo, Isabelle L., et al.
Publicado: (2014)

Nuclear delivery of NFκB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging
por: Breuzard, Gilles, et al.
Publicado: (2008)

Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects
por: Barbier, Pascale, et al.
Publicado: (2019)

Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target
por: Oakley, Sebastian S., et al.
Publicado: (2020)

Investigation of the Therapeutic Effect of Doxorubicin Combined With Focused Shockwave on Glioblastoma
por: Liao, Wei-Hao, et al.
Publicado: (2021)

Role of Tau protein in long COVID and potential therapeutic targets
por: Marwaha, Bharat
Publicado: (2023)

Angiogenesis and Its Targeting in Glioblastoma with Focus on Clinical Approaches
por: Daneshimehr, Fatemeh, et al.
Publicado: (2022)

Pharmacological targets for the induction of ferroptosis: Focus on Neuroblastoma and Glioblastoma
por: Ferrada, Luciano, et al.
Publicado: (2022)

Gemcitabine: An Alternative Treatment for Oxaliplatin-Resistant Colorectal Cancer
por: Chocry, Mathieu, et al.
Publicado: (2022)

Glioblastoma Stem Cells as a New Therapeutic Target for Glioblastoma
por: Kalkan, Rasime
Publicado: (2015)

Focused ultrasound-aided immunomodulation in glioblastoma multiforme: a therapeutic concept
por: Cohen-Inbar, Or, et al.
Publicado: (2016)

Eph receptors as therapeutic targets in glioblastoma
por: Day, B W, et al.
Publicado: (2014)

HOTAIR is a therapeutic target in glioblastoma
por: Zhou, Xuan, et al.
Publicado: (2015)

Prolactin and its receptor as therapeutic targets in glioblastoma multiforme
por: Asad, Antonela Sofía, et al.
Publicado: (2019)

Oxidation of Са(2+)-Binding Domain of NADPH Oxidase 5 (NOX5): Toward Understanding the Mechanism of Inactivation of NOX5 by ROS
por: Petrushanko, Irina Yu, et al.
Publicado: (2016)

Tau as a potential therapeutic target for ischemic stroke
por: Chen, Xin, et al.
Publicado: (2019)

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?
por: Fichou, Yann, et al.
Publicado: (2019)

Mesenchymal Migration as a Therapeutic Target in Glioblastoma
por: Zhong, Jessie, et al.
Publicado: (2010)

SUMOylation in Glioblastoma: A Novel Therapeutic Target
por: Fox, Brandon M., et al.
Publicado: (2019)

EGFR and mTOR as therapeutic targets in glioblastoma
por: Ronellenfitsch, Michael W., et al.
Publicado: (2019)

Aptamer-Based In Vivo Therapeutic Targeting of Glioblastoma
por: Cesarini, Valeriana, et al.
Publicado: (2020)

Glioblastoma Multiforme: An Overview of Emerging Therapeutic Targets
por: Taylor, Olivia G., et al.
Publicado: (2019)

WNT Signaling as a Therapeutic Target for Glioblastoma
por: Latour, Michael, et al.
Publicado: (2021)

The Use of Targeted Cytokines as Cancer Therapeutics in Glioblastoma
por: Sooreshjani, Moloud, et al.
Publicado: (2023)

Pathogenic Tau Protein Species: Promising Therapeutic Targets for Ocular Neurodegenerative Diseases
por: Mishan, Mohammad Amir, et al.
Publicado: (2019)

Challenging Hurdles of Current Targeting in Glioblastoma: A Focus on Immunotherapeutic Strategies
por: Genoud, Vassilis, et al.
Publicado: (2021)

Focused ultrasound for the treatment of glioblastoma
por: Roberts, Jill W., et al.
Publicado: (2022)

Tau-focused therapy and tau transmission: Implications for Alzheimer’s Disease and related tauopathies
por: Trojanowski, John Q
Publicado: (2013)

The toxicity of tau in Alzheimer disease: turnover, targets and potential therapeutics
por: Pritchard, Susanne M, et al.
Publicado: (2011)

Tau: A Common Denominator and Therapeutic Target for Neurodegenerative Disorders
por: Maxan, Alexander, et al.
Publicado: (2018)

Identification of structural determinants on tau protein essential for its pathological function: novel therapeutic target for tau immunotherapy in Alzheimer’s disease
por: Kontsekova, Eva, et al.
Publicado: (2014)

Sonodynamic therapy and magnetic resonance-guided focused ultrasound: new therapeutic strategy in glioblastoma
por: Bonosi, Lapo, et al.
Publicado: (2023)

Integrin-αvβ3 as a Therapeutic Target in Glioblastoma: Back to the Future?
por: Echavidre, William, et al.
Publicado: (2022)

Current advances in the treatment of Alzheimer's disease: focused on considerations targeting Aβ and tau
por: Hong-Qi, Yang, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_no6qunv51ihun5ujokqquuvs25