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A Novel Ibuprofen Derivative and Its Complexes: Physicochemical Characterization, DFT Modeling, Docking, In Vitro Anti-Inflammatory Studies, and DNA Interaction

A novel derivative of ibuprofen and salicylaldehyde N′-(4-hydroxybenzylidene)-2-(4-isobutylphenyl) propane hydrazide (HL) was synthesized, followed by its complexation with Cu, Ni, Co, Gd, and Sm. The compounds obtained were characterized by (1)HNMR, mass spectrometry, UV-Vis spectroscopy, FT-IR spe...

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Detalles Bibliográficos
Autores principales:	Abbas, Abbas M., Aboelmagd, Ahmed, Kishk, Safaa M., Nasrallah, Hossam H., Boyd, Warren Christopher, Kalil, Haitham, Orabi, Adel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653649/ https://www.ncbi.nlm.nih.gov/pubmed/36364366 http://dx.doi.org/10.3390/molecules27217540

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