The Predictive and Prognostic Role of RAS–RAF–MEK–ERK Pathway Alterations in Breast Cancer: Revision of the Literature and Comparison with the Analysis of Cancer Genomic Datasets

SIMPLE SUMMARY: The RAS/RAF/MEK/ERK pathway is implicated in fundamental processes frequently altered in tumors, such as cell proliferation and survival. In breast cancer, it is rarely affected by genomic alterations, but it is activated by membrane receptors or by epigenetic phenomena or readjustme...

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Detalles Bibliográficos
Autores principales: Rocca, Andrea, Braga, Luca, Volpe, Maria Concetta, Maiocchi, Serena, Generali, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653766/
https://www.ncbi.nlm.nih.gov/pubmed/36358725
http://dx.doi.org/10.3390/cancers14215306

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