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High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation

Human-relevant tests to predict developmental toxicity are urgently needed. A currently intensively studied approach makes use of differentiating human stem cells to measure chemically-induced deviations of the normal developmental program, as in a recent study based on cardiac differentiation (UKK2...

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Detalles Bibliográficos
Autores principales: Seidel, Florian, Cherianidou, Anna, Kappenberg, Franziska, Marta, Miriam, Dreser, Nadine, Blum, Jonathan, Waldmann, Tanja, Blüthgen, Nils, Meisig, Johannes, Madjar, Katrin, Henry, Margit, Rotshteyn, Tamara, Scholtz-Illigens, Andreas, Marchan, Rosemarie, Edlund, Karolina, Leist, Marcel, Rahnenführer, Jörg, Sachinidis, Agapios, Hengstler, Jan Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653768/
https://www.ncbi.nlm.nih.gov/pubmed/36359802
http://dx.doi.org/10.3390/cells11213404