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Multifunctional Derivatives of Spiropyrrolidine Tethered Indeno-Quinoxaline Heterocyclic Hybrids as Potent Antimicrobial, Antioxidant and Antidiabetic Agents: Design, Synthesis, In Vitro and In Silico Approaches

To combat emerging antimicrobial-resistant microbes, there is an urgent need to develop new antimicrobials with better therapeutic profiles. For this, a series of 13 new spiropyrrolidine derivatives were designed, synthesized, characterized and evaluated for their in vitro antimicrobial, antioxidant...

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Detalles Bibliográficos
Autores principales: Bouali, Nouha, Hammouda, Manel Ben, Ahmad, Iqrar, Ghannay, Siwar, Thouri, Amira, Dbeibia, Amal, Patel, Harun, Hamadou, Walid Sabri, Hosni, Karim, Snoussi, Mejdi, Adnan, Mohd, Hassan, Md Imtaiyaz, Noumi, Emira, Aouadi, Kaïss, Kadri, Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653804/
https://www.ncbi.nlm.nih.gov/pubmed/36364077
http://dx.doi.org/10.3390/molecules27217248