Cargando…

Intravenous Nicotinamide Riboside Administration Has a Cardioprotective Effect in Chronic Doxorubicin-Induced Cardiomyopathy

Doxorubicin, which is widely used to treat a broad spectrum of malignancies, has pronounced dose-dependent side effects leading to chronic heart failure development. Nicotinamide riboside (NR) is one of the promising candidates for leveling the cardiotoxic effect. In the present work, we performed a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Podyacheva, Ekaterina, Semenova, Natalia, Zinserling, Vsevolod, Mukhametdinova, Daria, Goncharova, Irina, Zelinskaya, Irina, Sviridov, Eric, Martynov, Michael, Osipova, Svetlana, Toropova, Yana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653852/ https://www.ncbi.nlm.nih.gov/pubmed/36361882 http://dx.doi.org/10.3390/ijms232113096

Ejemplares similares

Nicotinamide Riboside for the Prevention and Treatment of Doxorubicin Cardiomyopathy. Opportunities and Prospects
por: Podyacheva, Ekaterina, et al.
Publicado: (2021)

Influenza A(H1N1)pdm09 Virus Aggravates Pathology of Blood Vessels in Wistar Rats with Premorbid Acute Cardiomyopathy
por: Marchenko, Vladimir, et al.
Publicado: (2023)

Influenza A Virus Causes Histopathological Changes and Impairment in Functional Activity of Blood Vessels in Different Vascular Beds
por: Marchenko, Vladimir, et al.
Publicado: (2022)

SIRT1 activation and its effect on intercalated disc proteins as a way to reduce doxorubicin cardiotoxicity
por: Podyacheva, Ekaterina, et al.
Publicado: (2022)

Modeling Doxorubicin-Induced Cardiomyopathy With Fibrotic Myocardial Damage in Wistar Rats
por: Podyacheva, Ekaterina, et al.
Publicado: (2022)

Emerging Role of Nicotinamide Riboside in Health and Diseases
por: Sharma, Chiranjeev, et al.
Publicado: (2022)

Analysis of Models of Doxorubicin-Induced Cardiomyopathy in Rats and Mice. A Modern View From the Perspective of the Pathophysiologist and the Clinician
por: Podyacheva, Ekaterina Yu, et al.
Publicado: (2021)

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
por: Fletcher, Rachel S., et al.
Publicado: (2017)

The Role of NAD+, SIRTs Interactions in Stimulating and Counteracting Carcinogenesis
por: Podyacheva, Ekaterina, et al.
Publicado: (2023)

Nicotinamide Riboside and Dihydronicotinic Acid Riboside Synergistically Increase Intracellular NAD(+) by Generating Dihydronicotinamide Riboside
por: Ciarlo, Eleonora, et al.
Publicado: (2022)

Dihydronicotinamide riboside: synthesis from nicotinamide riboside chloride, purification and stability studies
por: Zarei, Amin, et al.
Publicado: (2021)

The Clinical Effects of Nicotinamide Riboside on Inflammatory Parameters
por: Kwon, Jun, et al.
Publicado: (2022)

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
por: Ratajczak, Joanna, et al.
Publicado: (2016)

Equilibrative Nucleoside Transporters Mediate the Import of Nicotinamide Riboside and Nicotinic Acid Riboside into Human Cells
por: Kropotov, Andrey, et al.
Publicado: (2021)

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
por: Trammell, Samuel A. J., et al.
Publicado: (2016)

The emergence of the nicotinamide riboside kinases in the regulation of NAD(+) metabolism
por: Fletcher, Rachel S, et al.
Publicado: (2018)

Nicotinamide Riboside—The Current State of Research and Therapeutic Uses
por: Mehmel, Mario, et al.
Publicado: (2020)

The effects of in ovo nicotinamide riboside dose on broiler myogenesis
por: Xu, Xiaoxing, et al.
Publicado: (2020)

New Crystalline Salts of Nicotinamide Riboside as Food Additives
por: Schabert, Günter, et al.
Publicado: (2021)

Synthesis, Stability, and Bioavailability of Nicotinamide Riboside Trioleate Chloride
por: Zarei, Amin, et al.
Publicado: (2021)

Nicotinamide Riboside Supports Brain Health: Assessing the Evidence
por: Nkrumah-Elie, Yasmeen, et al.
Publicado: (2022)

Nicotinamide, Nicotinamide Riboside and Nicotinic Acid—Emerging Roles in Replicative and Chronological Aging in Yeast
por: Orlandi, Ivan, et al.
Publicado: (2020)

Nicotinamide riboside has minimal impact on energy metabolism in mouse models of mild obesity
por: Cartwright, David M, et al.
Publicado: (2021)

Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+)
por: Tempel, Wolfram, et al.
Publicado: (2007)

Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice
por: Trammell, Samuel A.J., et al.
Publicado: (2016)

The NAD(+) precursor nicotinamide riboside decreases exercise performance in rats
por: Kourtzidis, Ioannis A., et al.
Publicado: (2016)

Balancing NAD(+) deficits with nicotinamide riboside: therapeutic possibilities and limitations
por: Cercillieux, Angelique, et al.
Publicado: (2022)

NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health
por: Alegre, Gabriela Fabiana Soares, et al.
Publicado: (2023)

The senotherapeutic nicotinamide riboside raises platelet nicotinamide adenine dinucleotide levels but cannot prevent storage lesion
por: Delabie, Willem, et al.
Publicado: (2019)

Syntheses and chemical properties of β-nicotinamide riboside and its analogues and derivatives
por: Makarov, Mikhail V, et al.
Publicado: (2019)

Nicotinamide riboside regulates inflammation and mitochondrial markers in AML12 hepatocytes
por: Lee, Hee Jae, et al.
Publicado: (2019)

SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside
por: Mukherjee, Sarmistha, et al.
Publicado: (2021)

Enzymatic and Chemical Syntheses of Vacor Analogs of Nicotinamide Riboside, NMN and NAD
por: Sverkeli, Lars Jansen, et al.
Publicado: (2021)

Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice
por: Schaefer, Patrick M., et al.
Publicado: (2022)

Nicotinamide Riboside Improves Ataxia Scores and Immunoglobulin Levels in Ataxia Telangiectasia
por: Veenhuis, Stefanie J.G., et al.
Publicado: (2021)

Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson’s disease
por: Gaare, Johannes J., et al.
Publicado: (2023)

Purine nucleoside phosphorylase controls nicotinamide riboside metabolism in mammalian cells
por: Kropotov, Andrey, et al.
Publicado: (2022)

Nicotinamide Riboside Preserves Ovarian Injury in an Experimental Sepsis Model in Rats
por: Selli, Jale, et al.
Publicado: (2023)

SUPPLEMENTATION WITH NICOTINAMIDE RIBOSIDE ATTENUATES T CELL EXHAUSTION AND IMPROVES SURVIVAL IN SEPSIS
por: Zhao, Guang-ju, et al.
Publicado: (2023)

What is really known about the effects of nicotinamide riboside supplementation in humans
por: Damgaard, Mads V., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qv4k71a8vsolbpllmg3crgfqsi