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A Polytetrafluoroethylene (PTFE) and Nano-Al(2)O(3) Based Composite Coating with a Bacteriostatic Effect against E. coli and Low Cytotoxicity

The problem of bacterial contamination through surfaces is important for the food industry. In this regard, there is a growing interest in new coatings based on nanoparticles that can provide a long-term antibacterial effect. Aluminum oxide nanoparticles are a good candidate for such coatings due to...

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Autores principales: Burmistrov, Dmitriy E., Serov, Dmitriy A., Simakin, Aleksander V., Baimler, Ilya V., Uvarov, Oleg V., Gudkov, Sergey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653981/
https://www.ncbi.nlm.nih.gov/pubmed/36365757
http://dx.doi.org/10.3390/polym14214764
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author Burmistrov, Dmitriy E.
Serov, Dmitriy A.
Simakin, Aleksander V.
Baimler, Ilya V.
Uvarov, Oleg V.
Gudkov, Sergey V.
author_facet Burmistrov, Dmitriy E.
Serov, Dmitriy A.
Simakin, Aleksander V.
Baimler, Ilya V.
Uvarov, Oleg V.
Gudkov, Sergey V.
author_sort Burmistrov, Dmitriy E.
collection PubMed
description The problem of bacterial contamination through surfaces is important for the food industry. In this regard, there is a growing interest in new coatings based on nanoparticles that can provide a long-term antibacterial effect. Aluminum oxide nanoparticles are a good candidate for such coatings due to their availability and good biocompatibility. In this study, a coating containing aluminum oxide nanoparticles was produced using polytetrafluoroethylene as a polymer matrix—a polymer that exhibits excellent mechanical and physicochemical properties and it is not toxic. The obtained coatings based on “liquid Teflon” containing various concentrations of nanoparticles (0.001–0.1 wt%) prevented the bacterial growth, and they did not exhibit a cytotoxicity on animal cells in vitro. Such coatings are designed not only to provide an antibacterial surface effect, but also to eliminate micro damages on surfaces that inevitably occur in the process of food production.
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spelling pubmed-96539812022-11-15 A Polytetrafluoroethylene (PTFE) and Nano-Al(2)O(3) Based Composite Coating with a Bacteriostatic Effect against E. coli and Low Cytotoxicity Burmistrov, Dmitriy E. Serov, Dmitriy A. Simakin, Aleksander V. Baimler, Ilya V. Uvarov, Oleg V. Gudkov, Sergey V. Polymers (Basel) Article The problem of bacterial contamination through surfaces is important for the food industry. In this regard, there is a growing interest in new coatings based on nanoparticles that can provide a long-term antibacterial effect. Aluminum oxide nanoparticles are a good candidate for such coatings due to their availability and good biocompatibility. In this study, a coating containing aluminum oxide nanoparticles was produced using polytetrafluoroethylene as a polymer matrix—a polymer that exhibits excellent mechanical and physicochemical properties and it is not toxic. The obtained coatings based on “liquid Teflon” containing various concentrations of nanoparticles (0.001–0.1 wt%) prevented the bacterial growth, and they did not exhibit a cytotoxicity on animal cells in vitro. Such coatings are designed not only to provide an antibacterial surface effect, but also to eliminate micro damages on surfaces that inevitably occur in the process of food production. MDPI 2022-11-07 /pmc/articles/PMC9653981/ /pubmed/36365757 http://dx.doi.org/10.3390/polym14214764 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Burmistrov, Dmitriy E.
Serov, Dmitriy A.
Simakin, Aleksander V.
Baimler, Ilya V.
Uvarov, Oleg V.
Gudkov, Sergey V.
A Polytetrafluoroethylene (PTFE) and Nano-Al(2)O(3) Based Composite Coating with a Bacteriostatic Effect against E. coli and Low Cytotoxicity
title A Polytetrafluoroethylene (PTFE) and Nano-Al(2)O(3) Based Composite Coating with a Bacteriostatic Effect against E. coli and Low Cytotoxicity
title_full A Polytetrafluoroethylene (PTFE) and Nano-Al(2)O(3) Based Composite Coating with a Bacteriostatic Effect against E. coli and Low Cytotoxicity
title_fullStr A Polytetrafluoroethylene (PTFE) and Nano-Al(2)O(3) Based Composite Coating with a Bacteriostatic Effect against E. coli and Low Cytotoxicity
title_full_unstemmed A Polytetrafluoroethylene (PTFE) and Nano-Al(2)O(3) Based Composite Coating with a Bacteriostatic Effect against E. coli and Low Cytotoxicity
title_short A Polytetrafluoroethylene (PTFE) and Nano-Al(2)O(3) Based Composite Coating with a Bacteriostatic Effect against E. coli and Low Cytotoxicity
title_sort polytetrafluoroethylene (ptfe) and nano-al(2)o(3) based composite coating with a bacteriostatic effect against e. coli and low cytotoxicity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653981/
https://www.ncbi.nlm.nih.gov/pubmed/36365757
http://dx.doi.org/10.3390/polym14214764
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