Substitutional Diversity-Oriented Synthesis and In Vitro Anticancer Activity of Framework-Integrated Estradiol-Benzisoxazole Chimeras

Hybridization of steroids and other pharmacophores often modifies the bioactivity of the parent compounds, improving selectivity and side effect profile. In this study, estradiol and 3′-(un)substituted benzisoxazole moieties were combined into novel molecules by structural integration of their aroma...

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Detalles Bibliográficos
Autores principales: Kovács, Ferenc, Adamecz, Dóra Izabella, Nagy, Ferenc István, Papp, Benedek, Kiricsi, Mónika, Frank, Éva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654004/
https://www.ncbi.nlm.nih.gov/pubmed/36364293
http://dx.doi.org/10.3390/molecules27217456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654004/
https://www.ncbi.nlm.nih.gov/pubmed/36364293
http://dx.doi.org/10.3390/molecules27217456

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