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SIRT1 Promotes Host Protective Immunity against Toxoplasma gondii by Controlling the FoxO-Autophagy Axis via the AMPK and PI3K/AKT Signalling Pathways

Sirtuin 1 (SIRT1) regulates cellular processes by deacetylating non-histone targets, including transcription factors and intracellular signalling mediators; thus, its abnormal activation is closely linked to the pathophysiology of several diseases. However, its function in Toxoplasma gondii infectio...

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Detalles Bibliográficos
Autores principales: Lee, Jina, Kim, Jinju, Lee, Jae-Hyung, Choi, Yong Min, Choi, Hyeonil, Cho, Hwan-Doo, Cha, Guang-Ho, Lee, Young-Ha, Jo, Eun-Kyeong, Park, Byung-Hyun, Yuk, Jae-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654124/
https://www.ncbi.nlm.nih.gov/pubmed/36362370
http://dx.doi.org/10.3390/ijms232113578