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SIRT1 Promotes Host Protective Immunity against Toxoplasma gondii by Controlling the FoxO-Autophagy Axis via the AMPK and PI3K/AKT Signalling Pathways
Sirtuin 1 (SIRT1) regulates cellular processes by deacetylating non-histone targets, including transcription factors and intracellular signalling mediators; thus, its abnormal activation is closely linked to the pathophysiology of several diseases. However, its function in Toxoplasma gondii infectio...
Autores principales: | Lee, Jina, Kim, Jinju, Lee, Jae-Hyung, Choi, Yong Min, Choi, Hyeonil, Cho, Hwan-Doo, Cha, Guang-Ho, Lee, Young-Ha, Jo, Eun-Kyeong, Park, Byung-Hyun, Yuk, Jae-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654124/ https://www.ncbi.nlm.nih.gov/pubmed/36362370 http://dx.doi.org/10.3390/ijms232113578 |
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