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Synthetic Optimizations for Gram-Scale Preparation of 1-O-Methyl d-Glycero-α-d-gluco-heptoside 7-Phosphate from d-Glucose

Heptose phosphates—unique linkers between endotoxic lipid A and O-antigen in the bacterial membrane—are pathogen-associated molecular patterns recognized by the receptors of the innate immune system. Understanding the mechanisms of immune system activation is important for the development of therape...

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Detalles Bibliográficos
Autores principales:	Potapov, Konstantin V., Novikov, Roman A., Solyev, Pavel N., Kochetkov, Sergey N., Makarov, Alexander A., Mitkevich, Vladimir A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654166/ https://www.ncbi.nlm.nih.gov/pubmed/36364355 http://dx.doi.org/10.3390/molecules27217534

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