Magnesium Isoglycyrrhizinate Reduces the Target-Binding Amount of Cisplatin to Mitochondrial DNA and Renal Injury through SIRT3

Nephrotoxicity is the dose-limiting factor of cisplatin treatment. Magnesium isoglycyrrhizinate (MgIG) has been reported to ameliorate renal ischemia–reperfusion injury. This study aimed to investigate the protective effect and possible mechanisms of MgIG against cisplatin-induced nephrotoxicity fro...

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Detalles Bibliográficos
Autores principales: Wang, Xinyu, Zhu, Hutailong, Hu, Jiayin, Li, Haobin, Guo, Suhan, Chen, Bin, Liu, Changxiao, Wang, Guangji, Zhou, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654254/
https://www.ncbi.nlm.nih.gov/pubmed/36361883
http://dx.doi.org/10.3390/ijms232113093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654254/
https://www.ncbi.nlm.nih.gov/pubmed/36361883
http://dx.doi.org/10.3390/ijms232113093

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