Expression of DNA Methyltransferase 3B Isoforms Is Associated with DNA Satellite 2 Hypomethylation and Clinical Prognosis in Advanced High-Grade Serous Ovarian Carcinoma

Alterations in DNA methylation are critical for the carcinogenesis of ovarian tumors, especially ovarian carcinoma (OC). DNMT3B, a de novo DNA methyltransferase (DNMT), encodes for fifteen spliced protein products or isoforms. DNMT3B isoforms lack exons for the catalytic domain, with functional cons...

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Detalles Bibliográficos
Autores principales: Del Castillo Falconi, Victor M., Díaz-Chávez, José, Torres-Arciga, Karla, Luna-Maldonado, Fernando, Gudiño-Gomez, Adriana A., Pedroza-Torres, Abraham, Castro-Hernández, Clementina, Cantú de León, David, Herrera, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654283/
https://www.ncbi.nlm.nih.gov/pubmed/36361550
http://dx.doi.org/10.3390/ijms232112759

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