Upregulation of Na(v)1.6 Mediated by the p38 MAPK Pathway in the Dorsal Root Ganglia Contributes to Cancer-Induced Bone Pain in Rats

Cancer-induced bone pain (CIBP) occurs frequently among advanced cancer patients. Voltage-gated sodium channels (VGSCs) have been associated with chronic pain, but how VGSCs function in CIBP is poorly understood. Here, we aimed to investigate the specific role of VGSCs in the dorsal root ganglia (DR...

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Detalles Bibliográficos
Autores principales: Lin, Mingxue, Chen, Xiaohui, Wu, Shuyan, Chen, Pinzhong, Wan, Haiyang, Ma, Simeng, Lin, Na, Liao, Yanling, Zheng, Ting, Jiang, Jundan, Zheng, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654392/
https://www.ncbi.nlm.nih.gov/pubmed/36359772
http://dx.doi.org/10.3390/cells11213375

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