Altering Brain Amyloidosis by Intra-Lingual and Extra-Nasal Exposure of Aβ Aggregates

Extensive experimental and human-derived evidence suggest that misfolded Aβ particles spread similarly to infectious prions. Moreover, peripheral administration of Aβ seeds accelerates brain amyloidosis in both susceptible experimental animals and humans. The mechanisms and elements governing the tr...

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Detalles Bibliográficos
Autores principales: Gamez, Nazaret, Bravo-Alegria, Javiera, Huang, Yumeng, Perez-Urrutia, Nelson, Dongarwar, Deepa, Soto, Claudio, Morales, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654398/
https://www.ncbi.nlm.nih.gov/pubmed/36359840
http://dx.doi.org/10.3390/cells11213442

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