Cargando…

Inhibitory Effect of Isoliquiritigenin in Niemann-Pick C1-Like 1-Mediated Cholesterol Uptake

Isoliquiritigenin (ISL) is a flavonoid with a chalcone structure extracted from the natural herb Glycyrrhiza glabra. Its anti-inflammatory, antibacterial, antioxidant, and anticancer activities have been extensively studied. Moreover, ISL also possess hypolipidemic and atherosclerosis-reducing effec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Jun, Liu, Wenjing, Liang, Bing, Shi, Lingyu, Yang, Shanbo, Meng, Jingsen, Chang, Jing, Hu, Xiaokun, Zhang, Renshuai, Xing, Dongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654431/ https://www.ncbi.nlm.nih.gov/pubmed/36364321 http://dx.doi.org/10.3390/molecules27217494

Ejemplares similares

First Discovery of Cholesterol-Lowering Activity of Parthenolide as NPC1L1 Inhibitor
por: Liu, Wenjing, et al.
Publicado: (2022)

The role of NPC1L1 in cancer
por: Zhang, Renshuai, et al.
Publicado: (2022)

Recent Advances on the Role of ATGL in Cancer
por: Zhang, Renshuai, et al.
Publicado: (2022)

Research progress on antitumor activity of XRP44X and analogues as microtubule targeting agents
por: Wang, Chao, et al.
Publicado: (2023)

Design, synthesis and biological evaluation of 9-aryl-5H-pyrido[4,3-b]indole derivatives as potential tubulin polymerization inhibitors
por: Shi, Lingyu, et al.
Publicado: (2022)

Advances in antitumor research of CA-4 analogs carrying quinoline scaffold
por: Wang, Chao, et al.
Publicado: (2022)

Design, synthesis and biological evaluation of novel diarylpyridine derivatives as tubulin polymerisation inhibitors
por: Yang, Shanbo, et al.
Publicado: (2022)

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1
por: Carette, Jan E., et al.
Publicado: (2011)

Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1
por: Trinh, Michael Nguyen, et al.
Publicado: (2018)

The prognostic value of Niemann-Pick C1-like protein 1 and Niemann-Pick disease type C2 in hepatocellular carcinoma
por: Chen, Ke-Ji, et al.
Publicado: (2018)

PKC Activation in Niemann Pick C1 Cells Restores Subcellular Cholesterol Transport
por: Tamari, Farshad, et al.
Publicado: (2013)

Baculovirus Utilizes Cholesterol Transporter NIEMANN–Pick C1 for Host Cell Entry
por: Li, Zhihong, et al.
Publicado: (2019)

Intestinal and Hepatic Niemann-Pick C1-Like 1
por: Park, Sung-Woo
Publicado: (2013)

Mitochondrial Cholesterol in Alzheimer's Disease and Niemann–Pick Type C Disease
por: Torres, Sandra, et al.
Publicado: (2019)

Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection
por: Gong, Xin, et al.
Publicado: (2016)

Reduction of VLDL Secretion Decreases Cholesterol Excretion in Niemann-Pick C1-Like 1 Hepatic Transgenic Mice
por: Marshall, Stephanie M., et al.
Publicado: (2014)

Luteolin and Quercetin Affect the Cholesterol Absorption Mediated by Epithelial Cholesterol Transporter Niemann–Pick C1-Like 1 in Caco-2 Cells and Rats
por: Nekohashi, Mari, et al.
Publicado: (2014)

HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts
por: Pipalia, Nina H., et al.
Publicado: (2021)

Activation Mobilizes the Cholesterol in the Late Endosomes-Lysosomes of Niemann Pick Type C Cells
por: Lange, Yvonne, et al.
Publicado: (2012)

Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor
por: Sainz, Bruno, et al.
Publicado: (2012)

Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts
por: Cruz, Dana L., et al.
Publicado: (2021)

Niemann-Pick disease type C
por: Vanier, Marie T
Publicado: (2010)

Stem Cells and Niemann Pick Disease
por: Andolina, Marino
Publicado: (2014)

Stem Cells in Niemann-Pick Disease
por: Kim, Sun-Jung, et al.
Publicado: (2008)

Niemann-Pick disease and platelet dysfunction
Publicado: (2012)

Erratum: Figure Correction. Intestinal and Hepatic Niemann-Pick C1-Like 1
por: Park, Sung-Woo
Publicado: (2013)

Lysosomal-specific Cholesterol Reduction by Biocleavable Polyrotaxanes for Ameliorating Niemann-Pick Type C Disease
por: Tamura, Atsushi, et al.
Publicado: (2014)

Laboratory diagnosis of the Niemann-Pick type C disease: an inherited neurodegenerative disorder of cholesterol metabolism
por: Sitarska, Dominika, et al.
Publicado: (2019)

Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation
por: Dominko, Kristina, et al.
Publicado: (2021)

Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann–Pick disease type C treatment
por: Yamada, Yusei, et al.
Publicado: (2023)

Lysosomal and Mitochondrial Liaisons in Niemann-Pick Disease
por: Torres, Sandra, et al.
Publicado: (2017)

Niemann-Pick Disease: An Approach for Diagnosis in Adulthood
por: Patiño-Escobar, Bonell, et al.
Publicado: (2019)

Olfactory Deficits in Niemann-Pick Type C1 (NPC1) Disease
por: Hovakimyan, Marina, et al.
Publicado: (2013)

Niemann-Pick C1 Is Essential for Ebolavirus Replication and Pathogenesis In Vivo
por: Herbert, Andrew S., et al.
Publicado: (2015)

Defects in the retina of Niemann-pick type C 1 mutant mice
por: Yan, Xin, et al.
Publicado: (2014)

Defective platelet function in Niemann‐Pick disease type C1
por: Chen, Oscar C. W., et al.
Publicado: (2020)

The inhibitory effect of isoliquiritigenin on human platelets in vitro
por: Wu, Yingying, et al.
Publicado: (2023)

Transcriptional regulation of Niemann-Pick C1-like 1 gene by liver receptor homolog-1
por: Lee, Eui Sup, et al.
Publicado: (2015)

The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts
Publicado: (1989)

Visualization of cholesterol deposits in lysosomes of Niemann-Pick type C fibroblasts using recombinant perfringolysin O
por: Kwiatkowska, Katarzyna, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bf0kr5fsj6c59kr46bkmu65rum