Cargando…

Anti-Cancer and Anti-Inflammatory Activities of a Short Molecule, PS14 Derived from the Virulent Cellulose Binding Domain of Aphanomyces invadans, on Human Laryngeal Epithelial Cells and an In Vivo Zebrafish Embryo Model

In this study, the anti-cancer and anti-inflammatory activities of PS14, a short peptide derived from the cellulase binding domain of pathogenic fungus, Aphanomyces invadans, have been evaluated, in vitro and in vivo. Bioinformatics analysis of PS14 revealed the physicochemical properties and the we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Velayutham, Manikandan, Sarkar, Purabi, Sudhakaran, Gokul, Al-Ghanim, Khalid Abdullah, Maboob, Shahid, Juliet, Annie, Guru, Ajay, Muthupandian, Saravanan, Arockiaraj, Jesu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654460/ https://www.ncbi.nlm.nih.gov/pubmed/36364155 http://dx.doi.org/10.3390/molecules27217333

Ejemplares similares

Aquatic Peptide: The Potential Anti-Cancer and Anti-Microbial Activity of GE18 Derived from Pathogenic Fungus Aphanomyces invadans
por: Velayutham, Manikandan, et al.
Publicado: (2023)

Mitochondrial genomes and comparative genomics of Aphanomyces astaci and Aphanomyces invadans
por: Makkonen, Jenny, et al.
Publicado: (2016)

Editing the genome of Aphanomyces invadans using CRISPR/Cas9
por: Majeed, Muhammad, et al.
Publicado: (2018)

Experimental infection of Aphanomyces invadans and susceptibility in seven species of tropical fish
por: Afzali, Seyedeh F., et al.
Publicado: (2015)

Molecular insights into the mechanisms of susceptibility of Labeo rohita against oomycete Aphanomyces invadans
por: Pradhan, P. K., et al.
Publicado: (2020)

In vitro investigations on extracellular proteins secreted by Aphanomyces invadans, the causative agent of epizootic ulcerative syndrome
por: Majeed, Muhammad, et al.
Publicado: (2017)

Development and standardization of a monoclonal antibody-based rapid flow-through immunoassay for the detection of Aphanomyces invadans in the field
por: Adil, B, et al.
Publicado: (2013)

Immunomodulatory Potency of Eclipta alba (Bhringaraj) Leaf Extract in Heteropneustes fossilis against Oomycete Pathogen, Aphanomyces invadans
por: Kumar, Vikash, et al.
Publicado: (2023)

Carbapenem-resistant Pseudomonas aeruginosa in intensive care units increase mortality as an emerging global threat
por: Saravanan, Muthupandian, et al.
Publicado: (2023)

Development of a rapid and sensitive real-time diagnostic assay to detect and quantify Aphanomyces invadans, the causative agent of epizootic ulcerative syndrome
por: Ho, Diem Tho, et al.
Publicado: (2023)

Role and mechanistic actions of protein kinase inhibitors as an effective drug target for cancer and COVID
por: Narayanan, J., et al.
Publicado: (2023)

PS9, Derived from an Aquatic Fungus Virulent Protein, Glycosyl Hydrolase, Arrests MCF-7 Proliferation by Regulating Intracellular Reactive Oxygen Species and Apoptotic Pathways
por: Velayutham, Manikandan, et al.
Publicado: (2023)

Ophthalmic Intervention of Naringenin Decreases Vascular Endothelial Growth Factor by Counteracting Oxidative Stress and Cellular Damage in In Vivo Zebrafish
por: Sudhakaran, Gokul, et al.
Publicado: (2023)

Conspectus on nanodiagnostics as an incipient platform for detection of oral potentially malignant disorders and oral squamous cell carcinoma
por: Shanmugam, Dilip K., et al.
Publicado: (2023)

Antioxidant molecular mechanism of adenosyl homocysteinase from cyanobacteria and its wound healing process in fibroblast cells
por: Sarkar, Purabi, et al.
Publicado: (2020)

AphanoDB: a genomic resource for Aphanomyces pathogens
por: Madoui, Mohammed-Amine, et al.
Publicado: (2007)

Polyphenolic Composition of Lentil Roots in Response to Infection by Aphanomyces euteiches
por: Bazghaleh, Navid, et al.
Publicado: (2018)

Functionalized Sulfur-Containing Heterocyclic Analogs Induce Sub-G1 Arrest and Apoptotic Cell Death of Laryngeal Carcinoma In Vitro
por: Haridevamuthu, B., et al.
Publicado: (2023)

Editorial: Anti-cancer bioactive molecules from microbial sources
por: Mishra, Bishwambhar, et al.
Publicado: (2023)

Genome-wide association mapping of partial resistance to Aphanomyces euteiches in pea
por: Desgroux, Aurore, et al.
Publicado: (2016)

Advanced Imaging for Quantitative Evaluation of Aphanomyces Root Rot Resistance in Lentil
por: Marzougui, Afef, et al.
Publicado: (2019)

RM12 similar to substance P from tachykinin of freshwater murrel Channa striatus influence intracellular ROS in vitro fish erythrocytes and developmental toxicity and antioxidant enzymes in vivo zebrafish embryo
por: Raju, Stefi V., et al.
Publicado: (2021)

Transcriptome of Aphanomyces euteiches: New Oomycete Putative Pathogenicity Factors and Metabolic Pathways
por: Gaulin, Elodie, et al.
Publicado: (2008)

Tracing the origin of the crayfish plague pathogen, Aphanomyces astaci, to the Southeastern United States
por: Martín-Torrijos, Laura, et al.
Publicado: (2021)

A Meta-Analysis to Determine the State of Biological Control of Aphanomyces Root Rot
por: Godebo, Ashebir T., et al.
Publicado: (2022)

Molecular Docking Studies on the Anti-viral Effects of Compounds From Kabasura Kudineer on SARS-CoV-2 3CL(pro)
por: Vincent, Savariar, et al.
Publicado: (2020)

Genetic and Pathogenicity Diversity of Aphanomyces euteiches Populations From Pea-Growing Regions in France
por: Quillévéré-Hamard, Anne, et al.
Publicado: (2018)

Effects of Lentil Genotype on the Colonization of Beneficial Trichoderma Species and Biocontrol of Aphanomyces Root Rot
por: Bazghaleh, Navid, et al.
Publicado: (2020)

Identification and Characterization of Bacteria-Derived Antibiotics for the Biological Control of Pea Aphanomyces Root Rot
por: Lai, Xiao, et al.
Publicado: (2022)

Resistance to the crayfish plague, Aphanomyces astaci (Oomycota) in the endangered freshwater crayfish species, Austropotamobius pallipes
por: Martín-Torrijos, Laura, et al.
Publicado: (2017)

A Comprehensive Assessment of the Secretome Responsible for Host Adaptation of the Legume Root Pathogen Aphanomyces euteiches
por: Kiselev, Andrei, et al.
Publicado: (2022)

The root pathogen Aphanomyces euteiches secretes modular proteases in pea apoplast during host infection
por: Kiselev, Andrei, et al.
Publicado: (2023)

Toxicity of Buprofezin on the Survival of Embryo and Larvae of African Catfish, Clarias gariepinus (Bloch)
por: Marimuthu, Kasi, et al.
Publicado: (2013)

Genomics analysis of Aphanomyces spp. identifies a new class of oomycete effector associated with host adaptation
por: Gaulin, Elodie, et al.
Publicado: (2018)

Complete Genome Sequence of a Pseudomonas simiae Strain with Biocontrol Potential against Aphanomyces Root Rot
por: Godebo, Ashebir T., et al.
Publicado: (2021)

Isolation and anti-microbial susceptibility pattern of group B Streptococcus among pregnant women attending antenatal clinics in Ayder Referral Hospital and Mekelle Health Center, Mekelle, Northern Ethiopia
por: Alemseged, Gebreselassie, et al.
Publicado: (2015)

Study on the Anti-Biodegradation Property of Tunicate Cellulose
por: Cheng, Yanan, et al.
Publicado: (2020)

Deciphering common and specific transcriptional immune responses in pea towards the oomycete pathogens Aphanomyces euteiches and Phytophthora pisi
por: Hosseini, Sara, et al.
Publicado: (2015)

Dissecting the Genetic Architecture of Aphanomyces Root Rot Resistance in Lentil by QTL Mapping and Genome-Wide Association Study
por: Ma, Yu, et al.
Publicado: (2020)

Host-pathogen coevolution drives innate immune response to Aphanomyces astaci infection in freshwater crayfish: transcriptomic evidence
por: Boštjančić, Ljudevit Luka, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dbvhop5h5vbpo4ui5m16oudhgi