Non-Muscle MLCK Contributes to Endothelial Cell Hyper-Proliferation through the ERK Pathway as a Mechanism for Vascular Remodeling in Pulmonary Hypertension

Pulmonary arterial hypertension (PAH) is characterized by endothelial dysfunction, uncontrolled proliferation and migration of pulmonary arterial endothelial cells leading to increased pulmonary vascular resistance resulting in great morbidity and poor survival. Bone morphogenetic protein receptor I...

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Detalles Bibliográficos
Autores principales: Anis, Mariam, Gonzales, Janae, Halstrom, Rachel, Baig, Noman, Humpal, Cat, Demeritte, Regaina, Epshtein, Yulia, Jacobson, Jeffrey R., Fraidenburg, Dustin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654627/
https://www.ncbi.nlm.nih.gov/pubmed/36362426
http://dx.doi.org/10.3390/ijms232113641

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