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Shuterin Enhances the Cytotoxicity of the Natural Killer Leukemia Cell Line KHYG-1 by Increasing the Expression Levels of Granzyme B and IFN-γ through the MAPK and Ras/Raf Signaling Pathways
Natural killer (NK) cell therapy is an emerging tool for cancer immunotherapy. NK cells are isolated from peripheral blood, and their number and activity are limited. Therefore, primary NK cells should be expanded substantially, and their proliferation and cytotoxicity must be enhanced. Shuterin is...
Autores principales: | Lin, Jen-Tsun, Chuang, Yi-Ching, Chen, Mu-Kuan, Lo, Yu-Sheng, Lin, Chia-Chieh, Ho, Hsin-Yu, Liu, Yen-Tze, Hsieh, Ming-Ju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654641/ https://www.ncbi.nlm.nih.gov/pubmed/36361609 http://dx.doi.org/10.3390/ijms232112816 |
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