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The Prognostic and Therapeutic Potential of DNA Damage Repair Pathway Alterations and Homologous Recombination Deficiency in Lung Cancer

SIMPLE SUMMARY: DNA-damage repair (DDR) gene alterations are a hallmark for cancer. The exploitation of DDR alterations has improved outcomes in breast, ovarian, pancreatic, and prostate cancers. However, little is known about the role of DDR alterations, leading to a homologous recombination defici...

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Autores principales:	Khaddour, Karam, Felipe Fernandez, Manuel, Khabibov, Marsel, Garifullin, Airat, Dressler, Danielle, Topchu, Iuliia, Patel, Jyoti D., Weinberg, Frank, Boumber, Yanis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654807/ https://www.ncbi.nlm.nih.gov/pubmed/36358724 http://dx.doi.org/10.3390/cancers14215305

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