Stearoyl CoA Desaturase-1 Silencing in Glioblastoma Cells: Phospholipid Remodeling and Cytotoxicity Enhanced upon Autophagy Inhibition

Modulation of lipid metabolism is a well-established cancer hallmark, and SCD1 has been recognized as a key enzyme in promoting cancer cell growth, including in glioblastoma (GBM), the deadliest brain tumor and a paradigm of cancer resistance. The central goal of this work was to identify, by MS, th...

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Detalles Bibliográficos
Autores principales: Morais, Catarina M., Cardoso, Ana M., Araújo, Ana Rita D., Reis, Ana, Domingues, Pedro, Domingues, Maria Rosário M., de Lima, Maria C. Pedroso, Jurado, Amália S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654881/
https://www.ncbi.nlm.nih.gov/pubmed/36361811
http://dx.doi.org/10.3390/ijms232113014

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