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A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body
This paper proposes a nanosensor structure consisting of a metal–insulator–metal (MIM) waveguide with a rectangular root and a double-ring (SRRDR) with a rectangular cavity. In this paper, the cause and internal mechanism of Fano resonance are investigated by the finite element method (FEM), and the...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655127/ https://www.ncbi.nlm.nih.gov/pubmed/36364566 http://dx.doi.org/10.3390/nano12213784 |
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author | Zhou, Guoquan Yan, Shubin Chen, Lili Zhang, Xiaoyu Shen, Lifang Liu, Pengwei Cui, Yang Liu, Jilai Li, Tingsong Ren, Yifeng |
author_facet | Zhou, Guoquan Yan, Shubin Chen, Lili Zhang, Xiaoyu Shen, Lifang Liu, Pengwei Cui, Yang Liu, Jilai Li, Tingsong Ren, Yifeng |
author_sort | Zhou, Guoquan |
collection | PubMed |
description | This paper proposes a nanosensor structure consisting of a metal–insulator–metal (MIM) waveguide with a rectangular root and a double-ring (SRRDR) with a rectangular cavity. In this paper, the cause and internal mechanism of Fano resonance are investigated by the finite element method (FEM), and the transport characteristics are optimized by changing various parameters of the structure. The results show that the structure can achieve double Fano resonance. Due to the destructive disturbance between the wideband mode of the inverted rectangle on the bus waveguide and the narrowband mode of the SRRDR, the output spectrum of the system shows an obvious asymmetric Fano diagram, and the structural parameters of the sensor have a great influence on the Fano resonance. By changing the sensitive parameters, the optimal sensitivity of the refractive index nanosensor is 2280 nm/RIU, and the coefficient of excellence (FOM) is 76.7. In addition, the proposed high-sensitivity nanosensor will be used to detect hemoglobin concentration in blood, which has positive applications for biosensors and has great potential for future nanosensing and optical integration systems. |
format | Online Article Text |
id | pubmed-9655127 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96551272022-11-15 A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body Zhou, Guoquan Yan, Shubin Chen, Lili Zhang, Xiaoyu Shen, Lifang Liu, Pengwei Cui, Yang Liu, Jilai Li, Tingsong Ren, Yifeng Nanomaterials (Basel) Article This paper proposes a nanosensor structure consisting of a metal–insulator–metal (MIM) waveguide with a rectangular root and a double-ring (SRRDR) with a rectangular cavity. In this paper, the cause and internal mechanism of Fano resonance are investigated by the finite element method (FEM), and the transport characteristics are optimized by changing various parameters of the structure. The results show that the structure can achieve double Fano resonance. Due to the destructive disturbance between the wideband mode of the inverted rectangle on the bus waveguide and the narrowband mode of the SRRDR, the output spectrum of the system shows an obvious asymmetric Fano diagram, and the structural parameters of the sensor have a great influence on the Fano resonance. By changing the sensitive parameters, the optimal sensitivity of the refractive index nanosensor is 2280 nm/RIU, and the coefficient of excellence (FOM) is 76.7. In addition, the proposed high-sensitivity nanosensor will be used to detect hemoglobin concentration in blood, which has positive applications for biosensors and has great potential for future nanosensing and optical integration systems. MDPI 2022-10-27 /pmc/articles/PMC9655127/ /pubmed/36364566 http://dx.doi.org/10.3390/nano12213784 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhou, Guoquan Yan, Shubin Chen, Lili Zhang, Xiaoyu Shen, Lifang Liu, Pengwei Cui, Yang Liu, Jilai Li, Tingsong Ren, Yifeng A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body |
title | A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body |
title_full | A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body |
title_fullStr | A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body |
title_full_unstemmed | A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body |
title_short | A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body |
title_sort | nano refractive index sensing structure for monitoring hemoglobin concentration in human body |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655127/ https://www.ncbi.nlm.nih.gov/pubmed/36364566 http://dx.doi.org/10.3390/nano12213784 |
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