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A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body

This paper proposes a nanosensor structure consisting of a metal–insulator–metal (MIM) waveguide with a rectangular root and a double-ring (SRRDR) with a rectangular cavity. In this paper, the cause and internal mechanism of Fano resonance are investigated by the finite element method (FEM), and the...

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Autores principales: Zhou, Guoquan, Yan, Shubin, Chen, Lili, Zhang, Xiaoyu, Shen, Lifang, Liu, Pengwei, Cui, Yang, Liu, Jilai, Li, Tingsong, Ren, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655127/
https://www.ncbi.nlm.nih.gov/pubmed/36364566
http://dx.doi.org/10.3390/nano12213784
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author Zhou, Guoquan
Yan, Shubin
Chen, Lili
Zhang, Xiaoyu
Shen, Lifang
Liu, Pengwei
Cui, Yang
Liu, Jilai
Li, Tingsong
Ren, Yifeng
author_facet Zhou, Guoquan
Yan, Shubin
Chen, Lili
Zhang, Xiaoyu
Shen, Lifang
Liu, Pengwei
Cui, Yang
Liu, Jilai
Li, Tingsong
Ren, Yifeng
author_sort Zhou, Guoquan
collection PubMed
description This paper proposes a nanosensor structure consisting of a metal–insulator–metal (MIM) waveguide with a rectangular root and a double-ring (SRRDR) with a rectangular cavity. In this paper, the cause and internal mechanism of Fano resonance are investigated by the finite element method (FEM), and the transport characteristics are optimized by changing various parameters of the structure. The results show that the structure can achieve double Fano resonance. Due to the destructive disturbance between the wideband mode of the inverted rectangle on the bus waveguide and the narrowband mode of the SRRDR, the output spectrum of the system shows an obvious asymmetric Fano diagram, and the structural parameters of the sensor have a great influence on the Fano resonance. By changing the sensitive parameters, the optimal sensitivity of the refractive index nanosensor is 2280 nm/RIU, and the coefficient of excellence (FOM) is 76.7. In addition, the proposed high-sensitivity nanosensor will be used to detect hemoglobin concentration in blood, which has positive applications for biosensors and has great potential for future nanosensing and optical integration systems.
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spelling pubmed-96551272022-11-15 A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body Zhou, Guoquan Yan, Shubin Chen, Lili Zhang, Xiaoyu Shen, Lifang Liu, Pengwei Cui, Yang Liu, Jilai Li, Tingsong Ren, Yifeng Nanomaterials (Basel) Article This paper proposes a nanosensor structure consisting of a metal–insulator–metal (MIM) waveguide with a rectangular root and a double-ring (SRRDR) with a rectangular cavity. In this paper, the cause and internal mechanism of Fano resonance are investigated by the finite element method (FEM), and the transport characteristics are optimized by changing various parameters of the structure. The results show that the structure can achieve double Fano resonance. Due to the destructive disturbance between the wideband mode of the inverted rectangle on the bus waveguide and the narrowband mode of the SRRDR, the output spectrum of the system shows an obvious asymmetric Fano diagram, and the structural parameters of the sensor have a great influence on the Fano resonance. By changing the sensitive parameters, the optimal sensitivity of the refractive index nanosensor is 2280 nm/RIU, and the coefficient of excellence (FOM) is 76.7. In addition, the proposed high-sensitivity nanosensor will be used to detect hemoglobin concentration in blood, which has positive applications for biosensors and has great potential for future nanosensing and optical integration systems. MDPI 2022-10-27 /pmc/articles/PMC9655127/ /pubmed/36364566 http://dx.doi.org/10.3390/nano12213784 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhou, Guoquan
Yan, Shubin
Chen, Lili
Zhang, Xiaoyu
Shen, Lifang
Liu, Pengwei
Cui, Yang
Liu, Jilai
Li, Tingsong
Ren, Yifeng
A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body
title A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body
title_full A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body
title_fullStr A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body
title_full_unstemmed A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body
title_short A Nano Refractive Index Sensing Structure for Monitoring Hemoglobin Concentration in Human Body
title_sort nano refractive index sensing structure for monitoring hemoglobin concentration in human body
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655127/
https://www.ncbi.nlm.nih.gov/pubmed/36364566
http://dx.doi.org/10.3390/nano12213784
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