Preclinical Evaluation of CRISPR-Edited CAR-NK-92 Cells for Off-the-Shelf Treatment of AML and B-ALL

Acute myeloid leukemia (AML) and B-cell acute lymphocytic leukemia (B-ALL) are severe blood malignancies affecting both adults and children. Chimeric antigen receptor (CAR)-based immunotherapies have proven highly efficacious in the treatment of leukemia. However, the challenge of the immune escape...

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Detalles Bibliográficos
Autores principales: Ureña-Bailén, Guillermo, Dobrowolski, Jérôme-Maurice, Hou, Yujuan, Dirlam, Alicia, Roig-Merino, Alicia, Schleicher, Sabine, Atar, Daniel, Seitz, Christian, Feucht, Judith, Antony, Justin S., Mohammadian Gol, Tahereh, Handgretinger, Rupert, Mezger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655234/
https://www.ncbi.nlm.nih.gov/pubmed/36361619
http://dx.doi.org/10.3390/ijms232112828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655234/
https://www.ncbi.nlm.nih.gov/pubmed/36361619
http://dx.doi.org/10.3390/ijms232112828

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