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Regulation of the Key Epithelial Cancer Suppressor miR-124 Function by Competing Endogenous RNAs

A decrease in the miR-124 expression was observed in various epithelial cancers. Like a classical suppressor, miR-124 can inhibit the translation of multiple oncogenic proteins. Epigenetic mechanisms play a significant role in the regulation of miR-124 expression and involve hypermethylation of the...

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Detalles Bibliográficos
Autores principales: Braga, Eleonora A., Fridman, Marina V., Burdennyy, Alexey M., Filippova, Elena A., Loginov, Vitaly I., Pronina, Irina V., Dmitriev, Alexey A., Kushlinskii, Nikolay E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655303/
https://www.ncbi.nlm.nih.gov/pubmed/36362406
http://dx.doi.org/10.3390/ijms232113620