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The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities

Humans have always been exposed to tiny particles via dust storms, volcanic ash, and other natural processes, and our bodily systems are well adapted to protect us from these potentially harmful external agents. However, technological advancement has dramatically increased the production of nanomete...

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Autores principales: Aloisi, Massimo, Rossi, Gianna, Colafarina, Sabrina, Guido, Maurizio, Cecconi, Sandra, Poma, Anna M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655349/
https://www.ncbi.nlm.nih.gov/pubmed/36360633
http://dx.doi.org/10.3390/ijerph192113748
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author Aloisi, Massimo
Rossi, Gianna
Colafarina, Sabrina
Guido, Maurizio
Cecconi, Sandra
Poma, Anna M. G.
author_facet Aloisi, Massimo
Rossi, Gianna
Colafarina, Sabrina
Guido, Maurizio
Cecconi, Sandra
Poma, Anna M. G.
author_sort Aloisi, Massimo
collection PubMed
description Humans have always been exposed to tiny particles via dust storms, volcanic ash, and other natural processes, and our bodily systems are well adapted to protect us from these potentially harmful external agents. However, technological advancement has dramatically increased the production of nanometer-sized particles or nanoparticles (NPs), and many epidemiological studies have confirmed a correlation between NP exposure and the onset of cardiovascular diseases and various cancers. Among the adverse effects on human health, in recent years, potential hazards of nanomaterials on female reproductive organs have received increasing concern. Several animal and human studies have shown that NPs can translocate to the ovary, uterus, and placenta, thus negatively impacting female reproductive potential and fetal health. However, NPs are increasingly being used for therapeutic purposes as tools capable of modifying the natural history of degenerative diseases. Here we briefly summarize the toxic effects of few but widely diffused NPs on female fertility and also the use of nanotechnologies as a new molecular approach for either specific pathological conditions, such as ovarian cancer and infertility, or the cryopreservation of gametes and embryos.
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spelling pubmed-96553492022-11-15 The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities Aloisi, Massimo Rossi, Gianna Colafarina, Sabrina Guido, Maurizio Cecconi, Sandra Poma, Anna M. G. Int J Environ Res Public Health Review Humans have always been exposed to tiny particles via dust storms, volcanic ash, and other natural processes, and our bodily systems are well adapted to protect us from these potentially harmful external agents. However, technological advancement has dramatically increased the production of nanometer-sized particles or nanoparticles (NPs), and many epidemiological studies have confirmed a correlation between NP exposure and the onset of cardiovascular diseases and various cancers. Among the adverse effects on human health, in recent years, potential hazards of nanomaterials on female reproductive organs have received increasing concern. Several animal and human studies have shown that NPs can translocate to the ovary, uterus, and placenta, thus negatively impacting female reproductive potential and fetal health. However, NPs are increasingly being used for therapeutic purposes as tools capable of modifying the natural history of degenerative diseases. Here we briefly summarize the toxic effects of few but widely diffused NPs on female fertility and also the use of nanotechnologies as a new molecular approach for either specific pathological conditions, such as ovarian cancer and infertility, or the cryopreservation of gametes and embryos. MDPI 2022-10-22 /pmc/articles/PMC9655349/ /pubmed/36360633 http://dx.doi.org/10.3390/ijerph192113748 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Aloisi, Massimo
Rossi, Gianna
Colafarina, Sabrina
Guido, Maurizio
Cecconi, Sandra
Poma, Anna M. G.
The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities
title The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities
title_full The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities
title_fullStr The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities
title_full_unstemmed The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities
title_short The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities
title_sort impact of metal nanoparticles on female reproductive system: risks and opportunities
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655349/
https://www.ncbi.nlm.nih.gov/pubmed/36360633
http://dx.doi.org/10.3390/ijerph192113748
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