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Comparison of Intermolecular Interactions of Irreversible and Reversible Inhibitors with Bruton’s Tyrosine Kinase via Molecular Dynamics Simulations

Bruton’s tyrosine kinase (BTK) is a key protein from the TEC family and is involved in B-cell lymphoma occurrence and development. Targeting BTK is therefore an effective strategy for B-cell lymphoma treatment. Since previous studies on BTK have been limited to structure-function analyses of static...

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Detalles Bibliográficos
Autores principales:	Yu, Xiangfan, Qiu, Simei, Sun, Dongshan, Guo, Pei, Li, Quhuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655453/ https://www.ncbi.nlm.nih.gov/pubmed/36364276 http://dx.doi.org/10.3390/molecules27217451

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