Cargando…

Comprehensive and Quantitative Analysis of the Changes in Proteomic and Phosphoproteomic Profiles during Stimulation and Repression of Steroidogenesis in MA-10 Leydig Cells †

Leydig cells produce testosterone, a hormone essential for male sex differentiation and spermatogenesis. The pituitary hormone, LH, stimulates testosterone production in Leydig cells by increasing the intracellular cAMP levels, which leads to the activation of various kinases and transcription facto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Demmouche, Zoheir B., Tremblay, Jacques J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655519/ https://www.ncbi.nlm.nih.gov/pubmed/36361638 http://dx.doi.org/10.3390/ijms232112846

Ejemplares similares

Mechanism of Action of an Environmentally Relevant Organochlorine Mixture in Repressing Steroid Hormone Biosynthesis in Leydig Cells †
por: Enangue Njembele, Annick N., et al.
Publicado: (2022)

The Effect of Cordycepin on Steroidogenesis and Apoptosis in MA-10 Mouse Leydig Tumor Cells
por: Pan, Bo-Syong, et al.
Publicado: (2011)

Dynamic Remodeling of Membranes and Their Lipids during Acute Hormone-Induced Steroidogenesis in MA-10 Mouse Leydig Tumor Cells
por: Venugopal, Sathvika, et al.
Publicado: (2021)

Mechanisms of MEHP Inhibitory Action and Analysis of Potential Replacement Plasticizers on Leydig Cell Steroidogenesis
por: Enangue Njembele, Annick N., et al.
Publicado: (2021)

Steroidogenesis and early response gene expression in MA-10 Leydig tumor cells following heterologous receptor down-regulation and cellular desensitization
por: Chen, Tsuey-Ming, et al.
Publicado: (2016)

Fatty acids suppress the steroidogenesis of the MA-10 mouse Leydig cell line by downregulating CYP11A1 and inhibiting late-stage autophagy
por: Huang, Chien, et al.
Publicado: (2021)

A 35-bp Conserved Region Is Crucial for Insl3 Promoter Activity in Mouse MA-10 Leydig Cells
por: Giner, Xavier C., et al.
Publicado: (2022)

Effects of Etomidate on the Steroidogenesis of Rat Immature Leydig Cells
por: Liu, Hua-Cheng, et al.
Publicado: (2015)

Slit/Robo signaling regulates Leydig cell steroidogenesis
por: Martinot, Emmanuelle, et al.
Publicado: (2021)

Molecular Mechanism of Isocupressic Acid Supresses MA-10 Cell Steroidogenesis
por: Tsui, Kuan-Hao, et al.
Publicado: (2012)

Fibroblast Growth Factor 9 Activates Akt and MAPK Pathways to Stimulate Steroidogenesis in Mouse Leydig Cells
por: Lai, Meng-Shao, et al.
Publicado: (2014)

Effects of the Yangjing Capsule Extract on Steroidogenesis and Apoptosis in Mouse Leydig Cells
por: Sun, Dalin, et al.
Publicado: (2012)

Jagged1 intracellular domain modulates steroidogenesis in testicular Leydig cells
por: Kumar, Sudeep, et al.
Publicado: (2020)

Prohibitin-1 plays a regulatory role in Leydig cell steroidogenesis
por: Bassi, Geetika, et al.
Publicado: (2022)

Gigantol Improves Cholesterol Metabolism and Progesterone Biosynthesis in MA-10 Leydig Cells
por: Basque, Audrey, et al.
Publicado: (2021)

Comparison of the Effects of Dibutyl and Monobutyl Phthalates on the Steroidogenesis of Rat Immature Leydig Cells
por: Li, Linxi, et al.
Publicado: (2016)

The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells
por: Leisegang, Kristian, et al.
Publicado: (2018)

Functional metabolite reserves and lipid homeostasis revealed by the MA-10 Leydig cell metabolome
por: Koganti, Prasanthi P, et al.
Publicado: (2022)

Calretinin Participates in Regulating Steroidogenesis by PLC-Ca(2+)-PKC Pathway in Leydig Cells
por: Xu, Wendan, et al.
Publicado: (2018)

Apoptotic effect of cordycepin combined with cisplatin and/or paclitaxel on MA-10 mouse Leydig tumor cells
por: Kang, Fu-Chi, et al.
Publicado: (2015)

Mitochondrial TSPO Deficiency Triggers Retrograde Signaling in MA-10 Mouse Tumor Leydig Cells
por: Fan, Jinjiang, et al.
Publicado: (2020)

Cordycepin Induced MA-10 Mouse Leydig Tumor Cell Apoptosis through Caspase-9 Pathway
por: Jen, Chun-Yi, et al.
Publicado: (2011)

Effect of chronic treatment with Rosiglitazone on Leydig cell steroidogenesis in rats: In vivo and ex vivo studies
por: Couto, Janaína A, et al.
Publicado: (2010)

Astaxanthin Protects Steroidogenesis from Hydrogen Peroxide-Induced Oxidative Stress in Mouse Leydig Cells
por: Wang, Jyun-Yuan, et al.
Publicado: (2015)

Steroidogenesis and VEGF Production Doesn't Alter in Leydig Cells within the Homeostatic Range of Testicular Temperature
por: Goyal, Atul Kumar, et al.
Publicado: (2018)

ESR1 inhibits hCG-induced steroidogenesis and proliferation of progenitor Leydig cells in mice
por: Oh, Yeong Seok, et al.
Publicado: (2017)

Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells
por: Sararols, Pauline, et al.
Publicado: (2021)

Developmentally-Dynamic Murine Brain Proteomes and Phosphoproteomes Revealed by Quantitative Proteomics
por: Doubleday, Peter F., et al.
Publicado: (2014)

A Testis-Specific Long Noncoding RNA, Start, Is a Regulator of Steroidogenesis in Mouse Leydig Cells
por: Otsuka, Kai, et al.
Publicado: (2021)

Arsenic compounds activate MAPK and inhibit Akt pathways to induce apoptosis in MA‐10 mouse Leydig tumor cells
por: Juan, Wei‐Sheng, et al.
Publicado: (2022)

Cordycepin inhibits ERK pathway to suppress FGF9-induced tumorigenesis with MA-10 mouse Leydig tumor cells
por: Chen, Li-Ching, et al.
Publicado: (2023)

Time-Course Changes of Steroidogenic Gene Expression and Steroidogenesis of Rat Leydig Cells after Acute Immobilization Stress
por: Lin, Han, et al.
Publicado: (2014)

Differential Susceptibility of Germ and Leydig Cells to Cadmium-Mediated Toxicity: Impact on Testis Structure, Adiponectin Levels, and Steroidogenesis
por: Cupertino, Marli C., et al.
Publicado: (2017)

Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis
por: Engeli, Roger T., et al.
Publicado: (2018)

BMI1 promotes steroidogenesis through maintaining redox homeostasis in mouse MLTC-1 and primary Leydig cells
por: Gao, Tingting, et al.
Publicado: (2020)

A Transcriptome-Wide Screen for mRNAs Enriched in Fetal Leydig Cells: CRHR1 Agonism Stimulates Rat and Mouse Fetal Testis Steroidogenesis
por: McDowell, Erin N., et al.
Publicado: (2012)

Comprehensive proteome and phosphoproteome profiling shows negligible influence of RNAlater on protein abundance and phosphorylation
por: Bae, Jingi, et al.
Publicado: (2019)

Comprehensive proteome, phosphoproteome and kinome characterization of luminal A breast cancer
por: Yang, Ganglong, et al.
Publicado: (2023)

Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer’s disease
por: Ping, Lingyan, et al.
Publicado: (2020)

Quantitative proteome and phosphoproteome datasets of DNA replication and mitosis in Saccharomyces cerevisiae
por: Rossio, Valentina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1m640bino9j9rn9pu2vgitnslr