In Silico Identification of Multi-Target Ligands as Promising Hit Compounds for Neurodegenerative Diseases Drug Development

The conventional treatment of neurodegenerative diseases (NDDs) is based on the “one molecule—one target” paradigm. To combat the multifactorial nature of NDDs, the focus is now shifted toward the development of small-molecule-based compounds that can modulate more than one protein target, known as...

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Detalles Bibliográficos
Autores principales: Alov, Petko, Stoimenov, Hristo, Lessigiarska, Iglika, Pencheva, Tania, Tzvetkov, Nikolay T., Pajeva, Ilza, Tsakovska, Ivanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655539/
https://www.ncbi.nlm.nih.gov/pubmed/36362434
http://dx.doi.org/10.3390/ijms232113650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655539/
https://www.ncbi.nlm.nih.gov/pubmed/36362434
http://dx.doi.org/10.3390/ijms232113650

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