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In Silico Identification of Multi-Target Ligands as Promising Hit Compounds for Neurodegenerative Diseases Drug Development
The conventional treatment of neurodegenerative diseases (NDDs) is based on the “one molecule—one target” paradigm. To combat the multifactorial nature of NDDs, the focus is now shifted toward the development of small-molecule-based compounds that can modulate more than one protein target, known as...
Autores principales: | Alov, Petko, Stoimenov, Hristo, Lessigiarska, Iglika, Pencheva, Tania, Tzvetkov, Nikolay T., Pajeva, Ilza, Tsakovska, Ivanka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655539/ https://www.ncbi.nlm.nih.gov/pubmed/36362434 http://dx.doi.org/10.3390/ijms232113650 |
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