Discovery of Highly Functionalized 5-hydroxy-2H-pyrrol-2-ones That Exhibit Antiestrogenic Effects in Breast and Endometrial Cancer Cells and Potentiate the Antitumoral Effect of Tamoxifen

SIMPLE SUMMARY: About 70% of the breast tumors diagnosed are estrogen receptor (ER)-positive and depend on estrogens and the interactions with their ER to grow and survive; their therapeutic treatment has a good clinical prognosis and effectiveness, but antitumoral treatment resistances and undesira...

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Detalles Bibliográficos
Autores principales: Guerra-Rodríguez, Miguel, López-Rojas, Priscila, Amesty, Ángel, Aranda-Tavío, Haidée, Brito-Casillas, Yeray, Estévez-Braun, Ana, Fernández-Pérez, Leandro, Guerra, Borja, Recio, Carlota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655618/
https://www.ncbi.nlm.nih.gov/pubmed/36358593
http://dx.doi.org/10.3390/cancers14215174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655618/
https://www.ncbi.nlm.nih.gov/pubmed/36358593
http://dx.doi.org/10.3390/cancers14215174

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