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Effects of Capsaicin and Capsiate on Endurance Performance: A Meta-Analysis

Several studies have explored the effects of capsaicin and capsiate on endurance performance, with conflicting findings. This systematic review aimed to perform a meta-analysis examining the effects of capsaicin and capsiate vs. placebo on endurance performance in humans. Seven databases were search...

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Autores principales: Grgic, Jozo, Memon, Aamir Raoof, Chen, Sitong, Ramirez-Campillo, Rodrigo, Barreto, Gabriel, Haugen, Markus Estifanos, Schoenfeld, Brad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655695/
https://www.ncbi.nlm.nih.gov/pubmed/36364793
http://dx.doi.org/10.3390/nu14214531
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author Grgic, Jozo
Memon, Aamir Raoof
Chen, Sitong
Ramirez-Campillo, Rodrigo
Barreto, Gabriel
Haugen, Markus Estifanos
Schoenfeld, Brad J.
author_facet Grgic, Jozo
Memon, Aamir Raoof
Chen, Sitong
Ramirez-Campillo, Rodrigo
Barreto, Gabriel
Haugen, Markus Estifanos
Schoenfeld, Brad J.
author_sort Grgic, Jozo
collection PubMed
description Several studies have explored the effects of capsaicin and capsiate on endurance performance, with conflicting findings. This systematic review aimed to perform a meta-analysis examining the effects of capsaicin and capsiate vs. placebo on endurance performance in humans. Seven databases were searched to find eligible studies. The effects of capsaicin and capsiate on aerobic endurance (e.g., time-trials or time-to-exhaustion tests), muscular endurance (e.g., repetitions performed to muscular failure), and rating of perceived exertion (RPE) were examined in a random-effects meta-analysis. Fourteen studies (n = 183) were included in the review. Most studies provided capsaicin or capsiate in the dose of 12 mg, 45 min before exercise. In the meta-analysis for aerobic endurance, there was no significant difference between the placebo and capsaicin/capsiate conditions (Cohen’s d: 0.04; 95% confidence interval: −0.16, 0.25; p = 0.69). In subgroup meta-analyses, there were no significant differences between the placebo and capsaicin/capsiate conditions when analyzing only studies that used time-trials (p = 0.20) or time-to-exhaustion tests (p = 0.80). In the meta-analysis for muscular endurance, a significant ergogenic effect of capsaicin/capsiate was found (Cohen’s d: 0.27; 95% confidence interval: 0.10, 0.43; p = 0.002). When analyzing set-specific effects, an ergogenic effect of capsaicin/capsiate was found in set 1, set 2, and set 3 (Cohen’s d: 0.21–29). Capsaicin/capsiate ingestion reduced RPE following muscular endurance (p = 0.03) but not aerobic endurance tests (p = 0.58). In summary, capsaicin/capsiate supplementation acutely enhances muscular endurance, while the effects on aerobic endurance are less clear.
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spelling pubmed-96556952022-11-15 Effects of Capsaicin and Capsiate on Endurance Performance: A Meta-Analysis Grgic, Jozo Memon, Aamir Raoof Chen, Sitong Ramirez-Campillo, Rodrigo Barreto, Gabriel Haugen, Markus Estifanos Schoenfeld, Brad J. Nutrients Review Several studies have explored the effects of capsaicin and capsiate on endurance performance, with conflicting findings. This systematic review aimed to perform a meta-analysis examining the effects of capsaicin and capsiate vs. placebo on endurance performance in humans. Seven databases were searched to find eligible studies. The effects of capsaicin and capsiate on aerobic endurance (e.g., time-trials or time-to-exhaustion tests), muscular endurance (e.g., repetitions performed to muscular failure), and rating of perceived exertion (RPE) were examined in a random-effects meta-analysis. Fourteen studies (n = 183) were included in the review. Most studies provided capsaicin or capsiate in the dose of 12 mg, 45 min before exercise. In the meta-analysis for aerobic endurance, there was no significant difference between the placebo and capsaicin/capsiate conditions (Cohen’s d: 0.04; 95% confidence interval: −0.16, 0.25; p = 0.69). In subgroup meta-analyses, there were no significant differences between the placebo and capsaicin/capsiate conditions when analyzing only studies that used time-trials (p = 0.20) or time-to-exhaustion tests (p = 0.80). In the meta-analysis for muscular endurance, a significant ergogenic effect of capsaicin/capsiate was found (Cohen’s d: 0.27; 95% confidence interval: 0.10, 0.43; p = 0.002). When analyzing set-specific effects, an ergogenic effect of capsaicin/capsiate was found in set 1, set 2, and set 3 (Cohen’s d: 0.21–29). Capsaicin/capsiate ingestion reduced RPE following muscular endurance (p = 0.03) but not aerobic endurance tests (p = 0.58). In summary, capsaicin/capsiate supplementation acutely enhances muscular endurance, while the effects on aerobic endurance are less clear. MDPI 2022-10-28 /pmc/articles/PMC9655695/ /pubmed/36364793 http://dx.doi.org/10.3390/nu14214531 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Grgic, Jozo
Memon, Aamir Raoof
Chen, Sitong
Ramirez-Campillo, Rodrigo
Barreto, Gabriel
Haugen, Markus Estifanos
Schoenfeld, Brad J.
Effects of Capsaicin and Capsiate on Endurance Performance: A Meta-Analysis
title Effects of Capsaicin and Capsiate on Endurance Performance: A Meta-Analysis
title_full Effects of Capsaicin and Capsiate on Endurance Performance: A Meta-Analysis
title_fullStr Effects of Capsaicin and Capsiate on Endurance Performance: A Meta-Analysis
title_full_unstemmed Effects of Capsaicin and Capsiate on Endurance Performance: A Meta-Analysis
title_short Effects of Capsaicin and Capsiate on Endurance Performance: A Meta-Analysis
title_sort effects of capsaicin and capsiate on endurance performance: a meta-analysis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655695/
https://www.ncbi.nlm.nih.gov/pubmed/36364793
http://dx.doi.org/10.3390/nu14214531
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