In Vitro and In Silico Analysis of New n-Butyl and Isobutyl Quinoxaline-7-carboxylate 1,4-di-N-oxide Derivatives against Trypanosoma cruzi as Trypanothione Reductase Inhibitors

American trypanosomiasis is a worldwide health problem that requires attention due to ineffective treatment options. We evaluated n-butyl and isobutyl quinoxaline-7-carboxylate 1,4-di-N-oxide derivatives against trypomastigotes of the Trypanosoma cruzi strains NINOA and INC-5. An in silico analysis...

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Detalles Bibliográficos
Autores principales: González-González, Alonzo, Sánchez-Sánchez, Oscar, Krauth-Siegel, R. Luise, Bolognesi, Maria Laura, Gớmez-Escobedo, Rogelio, Nogueda-Torres, Benjamín, Vázquez-Jiménez, Lenci K., Saavedra, Emma, Encalada, Rusely, Espinoza-Hicks, José Carlos, Paz-González, Alma D., Rivera, Gildardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655728/
https://www.ncbi.nlm.nih.gov/pubmed/36362102
http://dx.doi.org/10.3390/ijms232113315

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