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A Deep Learning-Based Model for Predicting Abnormal Liver Function in Workers in the Automotive Manufacturing Industry: A Cross-Sectional Survey in Chongqing, China

To identify the influencing factors and develop a predictive model for the risk of abnormal liver function in the automotive manufacturing industry works in Chongqing. Automotive manufacturing workers in Chongqing city surveyed during 2019–2021 were used as the study subjects. Logistic regression an...

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Autores principales: Ni, Linghao, Chen, Fengqiong, Ran, Ruihong, Li, Xiaoping, Jin, Nan, Zhang, Huadong, Peng, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655771/
https://www.ncbi.nlm.nih.gov/pubmed/36361178
http://dx.doi.org/10.3390/ijerph192114300
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author Ni, Linghao
Chen, Fengqiong
Ran, Ruihong
Li, Xiaoping
Jin, Nan
Zhang, Huadong
Peng, Bin
author_facet Ni, Linghao
Chen, Fengqiong
Ran, Ruihong
Li, Xiaoping
Jin, Nan
Zhang, Huadong
Peng, Bin
author_sort Ni, Linghao
collection PubMed
description To identify the influencing factors and develop a predictive model for the risk of abnormal liver function in the automotive manufacturing industry works in Chongqing. Automotive manufacturing workers in Chongqing city surveyed during 2019–2021 were used as the study subjects. Logistic regression analysis was used to identify the influencing factors of abnormal liver function. A restricted cubic spline model was used to further explore the influence of the length of service. Finally, a deep neural network-based model for predicting the risk of abnormal liver function among workers was developed. Of all 6087 study subjects, a total of 1018 (16.7%) cases were detected with abnormal liver function. Increased BMI, length of service, DBP, SBP, and being male were independent risk factors for abnormal liver function. The risk of abnormal liver function rises sharply with increasing length of service below 10 years. AUC values of the model were 0.764 (95% CI: 0.746–0.783) and 0.756 (95% CI: 0.727–0.786) in the training and test sets, respectively. The other four evaluation indices of the DNN model also achieved good values.
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spelling pubmed-96557712022-11-15 A Deep Learning-Based Model for Predicting Abnormal Liver Function in Workers in the Automotive Manufacturing Industry: A Cross-Sectional Survey in Chongqing, China Ni, Linghao Chen, Fengqiong Ran, Ruihong Li, Xiaoping Jin, Nan Zhang, Huadong Peng, Bin Int J Environ Res Public Health Article To identify the influencing factors and develop a predictive model for the risk of abnormal liver function in the automotive manufacturing industry works in Chongqing. Automotive manufacturing workers in Chongqing city surveyed during 2019–2021 were used as the study subjects. Logistic regression analysis was used to identify the influencing factors of abnormal liver function. A restricted cubic spline model was used to further explore the influence of the length of service. Finally, a deep neural network-based model for predicting the risk of abnormal liver function among workers was developed. Of all 6087 study subjects, a total of 1018 (16.7%) cases were detected with abnormal liver function. Increased BMI, length of service, DBP, SBP, and being male were independent risk factors for abnormal liver function. The risk of abnormal liver function rises sharply with increasing length of service below 10 years. AUC values of the model were 0.764 (95% CI: 0.746–0.783) and 0.756 (95% CI: 0.727–0.786) in the training and test sets, respectively. The other four evaluation indices of the DNN model also achieved good values. MDPI 2022-11-01 /pmc/articles/PMC9655771/ /pubmed/36361178 http://dx.doi.org/10.3390/ijerph192114300 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ni, Linghao
Chen, Fengqiong
Ran, Ruihong
Li, Xiaoping
Jin, Nan
Zhang, Huadong
Peng, Bin
A Deep Learning-Based Model for Predicting Abnormal Liver Function in Workers in the Automotive Manufacturing Industry: A Cross-Sectional Survey in Chongqing, China
title A Deep Learning-Based Model for Predicting Abnormal Liver Function in Workers in the Automotive Manufacturing Industry: A Cross-Sectional Survey in Chongqing, China
title_full A Deep Learning-Based Model for Predicting Abnormal Liver Function in Workers in the Automotive Manufacturing Industry: A Cross-Sectional Survey in Chongqing, China
title_fullStr A Deep Learning-Based Model for Predicting Abnormal Liver Function in Workers in the Automotive Manufacturing Industry: A Cross-Sectional Survey in Chongqing, China
title_full_unstemmed A Deep Learning-Based Model for Predicting Abnormal Liver Function in Workers in the Automotive Manufacturing Industry: A Cross-Sectional Survey in Chongqing, China
title_short A Deep Learning-Based Model for Predicting Abnormal Liver Function in Workers in the Automotive Manufacturing Industry: A Cross-Sectional Survey in Chongqing, China
title_sort deep learning-based model for predicting abnormal liver function in workers in the automotive manufacturing industry: a cross-sectional survey in chongqing, china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655771/
https://www.ncbi.nlm.nih.gov/pubmed/36361178
http://dx.doi.org/10.3390/ijerph192114300
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