CXCR4-CXCL12-CXCR7 and PD-1/PD-L1 in Pancreatic Cancer: CXCL12 Predicts Survival of Radically Resected Patients

Pancreatic ductal adenocarcinoma (PDAC) is currently the most deadly cancer. Although characterized by 5–20% of neoplastic cells in the highly fibrotic stroma, immunotherapy is not a valid option in PDAC treatment. As CXCR4-CXCL12 regulates tumor invasion and T-cell access and PD-1/PD-L1 controls im...

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Detalles Bibliográficos
Autores principales: D’Alterio, Crescenzo, Giardino, Alessandro, Scognamiglio, Giosuè, Butturini, Giovanni, Portella, Luigi, Guardascione, Giuseppe, Frigerio, Isabella, Montella, Marco, Gobbo, Stefano, Martignoni, Guido, Napolitano, Vincenzo, De Vita, Ferdinando, Tatangelo, Fabiana, Franco, Renato, Scala, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655815/
https://www.ncbi.nlm.nih.gov/pubmed/36359736
http://dx.doi.org/10.3390/cells11213340

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