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Biophysical Characterization of Adeno-Associated Virus Vectors Using Ion-Exchange Chromatography Coupled to Light Scattering Detectors
Ion-exchange chromatography coupled to light scattering detectors represents a fast and simple analytical method for the assessment of multiple critical quality attributes (CQA) in one single measurement. The determination of CQAs play a crucial role in Adeno-Associated Virus (AAV)-based gene therap...
Autores principales: | Wagner, Christina, Innthaler, Bernd, Lemmerer, Martin, Pletzenauer, Robert, Birner-Gruenberger, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655919/ https://www.ncbi.nlm.nih.gov/pubmed/36361506 http://dx.doi.org/10.3390/ijms232112715 |
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