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Siponimod Modulates the Reaction of Microglial Cells to Pro-Inflammatory Stimulation
Siponimod (Mayzent(®)), a sphingosine 1-phosphate receptor (S1PR) modulator which prevents lymphocyte egress from lymphoid tissues, is approved for the treatment of relapsing-remitting and active secondary progressive multiple sclerosis. It can cross the blood–brain barrier (BBB) and selectively bin...
Autores principales: | Gruchot, Joel, Lein, Ferdinand, Lewen, Isabel, Reiche, Laura, Weyers, Vivien, Petzsch, Patrick, Göttle, Peter, Köhrer, Karl, Hartung, Hans-Peter, Küry, Patrick, Kremer, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655930/ https://www.ncbi.nlm.nih.gov/pubmed/36362063 http://dx.doi.org/10.3390/ijms232113278 |
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